{"title":"壳聚糖负载cui催化2-卤代苯甲酸与脒级联反应合成喹唑啉酮。","authors":"Xuhong Zhao, Weishuang Li, Mengli Yang, Bojie Li, Yaoyao Zhang, Lizhen Huang, Lei Zhu","doi":"10.3762/bjoc.21.67","DOIUrl":null,"url":null,"abstract":"<p><p>A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield).</p>","PeriodicalId":8756,"journal":{"name":"Beilstein Journal of Organic Chemistry","volume":"21 ","pages":"839-844"},"PeriodicalIF":2.2000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051478/pdf/","citationCount":"0","resultStr":"{\"title\":\"Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones.\",\"authors\":\"Xuhong Zhao, Weishuang Li, Mengli Yang, Bojie Li, Yaoyao Zhang, Lizhen Huang, Lei Zhu\",\"doi\":\"10.3762/bjoc.21.67\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield).</p>\",\"PeriodicalId\":8756,\"journal\":{\"name\":\"Beilstein Journal of Organic Chemistry\",\"volume\":\"21 \",\"pages\":\"839-844\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051478/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Beilstein Journal of Organic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.3762/bjoc.21.67\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Beilstein Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.3762/bjoc.21.67","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones.
A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield).
期刊介绍:
The Beilstein Journal of Organic Chemistry is an international, peer-reviewed, Open Access journal. It provides a unique platform for rapid publication without any charges (free for author and reader) – Platinum Open Access. The content is freely accessible 365 days a year to any user worldwide. Articles are available online immediately upon publication and are publicly archived in all major repositories. In addition, it provides a platform for publishing thematic issues (theme-based collections of articles) on topical issues in organic chemistry.
The journal publishes high quality research and reviews in all areas of organic chemistry, including organic synthesis, organic reactions, natural product chemistry, structural investigations, supramolecular chemistry and chemical biology.