O I Patsap, O V Bratchikova, A V Babkina, M B Khabarova, S A Mikhalev, L M Mikhaleva
{"title":"[卵巢子宫内膜异位症纤维化的发病机制]。","authors":"O I Patsap, O V Bratchikova, A V Babkina, M B Khabarova, S A Mikhalev, L M Mikhaleva","doi":"10.17116/patol20258702173","DOIUrl":null,"url":null,"abstract":"<p><p>Endometriosis-associated fibrosis is a complex phenomenon, and the underlying mechanisms are still not fully understood. Fibrosis is invariably present in all forms of the disease and contributes to the classic endometriosis-associated symptoms such as chronic pelvic pain and infertility. The purpose of this literature review was to study the role of various cell populations, biological mechanisms and signaling pathways in inducing fibrogenesis of endometriosis lesions. PubMed and MEDLINE searched for studies published in English over the past 5 years that studied fibrosis in ovarian endometriosis.</p>","PeriodicalId":8548,"journal":{"name":"Arkhiv patologii","volume":"87 2","pages":"73-78"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Pathogenesis of fibrosis development in ovarian endometriosis].\",\"authors\":\"O I Patsap, O V Bratchikova, A V Babkina, M B Khabarova, S A Mikhalev, L M Mikhaleva\",\"doi\":\"10.17116/patol20258702173\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Endometriosis-associated fibrosis is a complex phenomenon, and the underlying mechanisms are still not fully understood. Fibrosis is invariably present in all forms of the disease and contributes to the classic endometriosis-associated symptoms such as chronic pelvic pain and infertility. The purpose of this literature review was to study the role of various cell populations, biological mechanisms and signaling pathways in inducing fibrogenesis of endometriosis lesions. PubMed and MEDLINE searched for studies published in English over the past 5 years that studied fibrosis in ovarian endometriosis.</p>\",\"PeriodicalId\":8548,\"journal\":{\"name\":\"Arkhiv patologii\",\"volume\":\"87 2\",\"pages\":\"73-78\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arkhiv patologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17116/patol20258702173\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arkhiv patologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17116/patol20258702173","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
[Pathogenesis of fibrosis development in ovarian endometriosis].
Endometriosis-associated fibrosis is a complex phenomenon, and the underlying mechanisms are still not fully understood. Fibrosis is invariably present in all forms of the disease and contributes to the classic endometriosis-associated symptoms such as chronic pelvic pain and infertility. The purpose of this literature review was to study the role of various cell populations, biological mechanisms and signaling pathways in inducing fibrogenesis of endometriosis lesions. PubMed and MEDLINE searched for studies published in English over the past 5 years that studied fibrosis in ovarian endometriosis.
期刊介绍:
The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.