超高分子量聚乙烯植入物改善犬髌骨韧带修复的生物力学性能:一项离体随机研究。

IF 1.3 3区 农林科学 Q2 VETERINARY SCIENCES
Romain Lamère, Maxime Guillet, Stefano Scotti, Chantal Ragetly, Thibaut Cachon
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引用次数: 0

摘要

目的:探讨3种不同修复方法对模拟犬髌骨中间韧带断裂的生物力学性能和失效模式的影响。方法:对9只成年杂交犬的后肢进行配对。研究设计是对尸体的实验性研究。髌骨韧带被横切并使用Bunnell和简单的中断的外延模式缝合。然后随机采用以下三种技术中的一种进行加固:髌骨周围缝合环远端固定于胫骨结节(1组),同一环结合阔筋膜条带(2组),或在髌骨近端缝合聚乙烯合成植入物并在远端用干涉螺钉固定(3组)。评估了屈服、峰值和失效载荷、刚度和失效模式。结果:每组6只后肢。合成种植体增强(组3)的屈服、峰值和失效负荷明显高于组1。2组与1、3组间无显著差异。结论:合成超高分子量聚乙烯植入物增强髌骨韧带修复比Bunnell缝合带髌周修复提供更大的抗拉强度。临床意义:使用合成超高分子量聚乙烯植入物可能为髌骨韧带修复提供一种可行的手术选择。需要进一步的研究来评估髌骨韧带损伤患者体内的长期预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ultrahigh-molecular-weight polyethylene implant improves biomechanical properties for patellar ligament repair in dogs: an ex vivo randomized study.

Objective: To assess the biomechanical properties and failure mode of 3 different repair methods in simulated midsubstance canine patella ligament rupture on cadavers.

Methods: The sample was paired hindlimbs of 9 adult mixed-breed dogs. The study design was an experimental study on cadavers. Patellar ligaments were transected and sutured using a Bunnell and simple interrupted epitendinous pattern. They were then randomly reinforced with 1 of 3 techniques: a circumpatellar suture loop anchored distally to the tibial tuberosity (group 1), the same loop combined with a fascia lata strip (group 2), or a polyethylene synthetic implant sutured over the patella proximally and secured distally with an interference screw (group 3). Yield, peak, and failure load, stiffness, and mode of failure were evaluated.

Results: Six hindlimbs were assigned to each group. Augmentation with the synthetic implant (group 3) showed significantly greater yield, peak, and failure load than group 1. There were no significant differences between group 2 and either group 1 or group 3.

Conclusions: Patellar ligament repair augmented with a synthetic ultrahigh-molecular-weight polyethylene implant offered greater tensile strength than a Bunnell suture with an adjunction of a circumpatellar repair.

Clinical relevance: The use of a synthetic ultrahigh-molecular-weight polyethylene implant may offer a viable surgical option for patellar ligament repair. Further studies are warranted to assess the long-term outcome in vivo in patients with injured patellar ligament.

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来源期刊
CiteScore
1.70
自引率
10.00%
发文量
186
审稿时长
3 months
期刊介绍: The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.
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