一项基于医院的布雷沙诺酮方案治疗患者的回顾性图表回顾研究。

IF 3.2 3区医学 Q2 PSYCHIATRY

Archives of Women's Mental Health Pub Date : 2025-05-02 DOI:10.1007/s00737-025-01588-9

Zobeida M Diaz, Margaret M Howard, Keyline V Moreno, Madilyn G Halwes, Cynthia L Battle

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引用次数: 0

摘要

目的：产后抑郁症（PPD）是美国最常见的分娩并发症，可以使用布雷沙诺酮治疗，布雷沙诺酮是一种静脉注射的异孕酮。方法：本回顾性图表回顾研究评估了64名产后妇女在现实世界中接受布雷沙诺酮输注治疗PPD的临床结果。结果：治疗与抑郁和焦虑症状的改善有关，71%的患者报告他们的PPD有显著改善。结论：虽然需要进一步的研究，但本研究支持布雷沙诺酮是治疗PPD的有效方法。

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A retrospective chart review study of patients treated in a hospital-based brexanolone program.

Purpose: Postpartum depression (PPD), the most common childbirth complication in the United States, can be treated using brexanolone, an intravenous form of allopregnanolone.

Methods: This retrospective chart review study evaluated clinical outcomes of 64 postpartum women who received brexanolone infusion for PPD in a real-world setting.

Results: Treatment was associated with improved depression and anxiety symptoms, and 71% of patients reported significant improvement in their PPD.

Conclusions: While further research is needed, this study supports brexanolone as an efficacious treatment for PPD.

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来源期刊

Archives of Women's Mental Health 医学-精神病学

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.