缺血性脑卒中患者臂间血压差与肾动脉狭窄发生率的关系。

IF 1.2 4区医学 Q4 PERIPHERAL VASCULAR DISEASE

Blood Pressure Monitoring Pub Date : 2025-04-09 DOI:10.1097/MBP.0000000000000753

Haiwen Li, Li Liu, Xianbi Tang, Kaiquan Jing, Chuzheng Pan

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引用次数: 0

摘要

目的：肾动脉狭窄（RAS）是缺血性脑卒中患者高血压和肾功能不全的潜在可逆性病因，与预后不良相关。臂间血压差（IABD）与动脉粥样硬化独立相关。本研究旨在探讨缺血性脑卒中患者RAS与IABD的关系。材料和方法：本研究是一项横断面观察性研究，研究对象为连续无RAS病史的缺血性脑卒中患者。在脑血管诊断程序后进行腹主动脉造影以筛查RAS。RAS定义为双肾动脉狭窄≥50%。进行单因素和多因素分析，探讨包括IABD在内的临床变量与RAS的关系。结果：422例缺血性脑卒中患者中，RAS≥62例（14.7%），收缩期IABD≥10 mmHg 142例（33.6%）。收缩期IABD≥10 mmHg的患者比无收缩期IABD的患者更容易发生RAS （59.7% vs 29.2%, P < 0.001）。logistic回归分析显示收缩期IABD≥10 mmHg与RAS独立相关(优势比3.67；95%置信区间：2.02-6.65；P < 0.001)。结论：测量臂间收缩压有助于识别缺血性脑卒中患者的RAS个体。

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Association between inter-arm blood pressure difference and prevalence of renal artery stenosis in patients with ischemic stroke.

Objective: Renal artery stenosis (RAS) which is a potentially reversible cause of hypertension and renal insufficiency is associated with poor prognosis in ischemic stroke patients. The inter-arm blood pressure difference (IABD) is independently related to the atherosclerosis of the arteries. This study was to evaluate the relationship of RAS with IABD in ischemic stroke patients.

Materials and methods: This study was a cross-sectional observational study of consecutive patients with ischemic stroke who had not a history of RAS. Abdominal aortography was performed to screen for RAS after the cerebrovascular diagnostic procedure. RAS was defined as the presence of ≥50% stenosis in either renal artery. Univariate and multivariate analysis were performed to investigate the association of the clinical variables including IABD with RAS.

Results: RAS and systolic IABD ≥ 10 mmHg were detected in 62 (14.7%) and 142 (33.6%) of all ischemic stroke patients (n = 422), respectively. Patients with systolic IABD ≥ 10 mmHg were more likely to have RAS than patients without (59.7 vs 29.2%, P < 0.001). The logistic regression analysis showed that systolic IABD ≥ 10 mmHg was independently associated with RAS (odds ratio, 3.67; 95% confidence interval: 2.02-6.65; P < 0.001).

Conclusion: Measuring SBP between arms may help identify individuals with RAS in ischemic stroke patients.

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来源期刊

Blood Pressure Monitoring 医学-外周血管病

CiteScore

2.00

自引率

7.70%

发文量

110

审稿时长

>12 weeks

期刊介绍： Blood Pressure Monitoring is devoted to original research in blood pressure measurement and blood pressure variability. It includes device technology, analytical methodology of blood pressure over time and its variability, clinical trials - including, but not limited to, pharmacology - involving blood pressure monitoring, blood pressure reactivity, patient evaluation, and outcomes and effectiveness research. This innovative journal contains papers dealing with all aspects of manual, automated, and ambulatory monitoring. Basic and clinical science papers are considered although the emphasis is on clinical medicine. Submitted articles undergo a preliminary review by the editor. Some articles may be returned to authors without further consideration. Those being considered for publication will undergo further assessment and peer-review by the editors and those invited to do so from a reviewer pool.