有或没有惩罚的离散时间竞争风险回归。

IF 1.4 4区 数学 Q3 BIOLOGY
Biometrics Pub Date : 2025-04-02 DOI:10.1093/biomtc/ujaf040
Tomer Meir, Malka Gorfine
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引用次数: 0

摘要

许多研究采用时间到事件数据的分析,其中包括竞争风险和正确审查。大多数方法和软件包都是面向分析来自连续故障时间分布的数据的。然而,故障时间数据有时可能是离散的,这要么是因为时间本身是离散的,要么是因为测量不精确。本文介绍了一种新的具有竞争事件的离散时间生存分析估计方法。所提出的方法提供了一个主要的关键优势超过现有的程序,并允许直接集成和应用广泛使用的正则化回归和筛选特征方法。我们通过一个全面的模拟研究来说明我们提出的方法的好处。此外,我们通过考虑3个相互竞争的事件:出院回家、转到其他医疗机构和院内死亡,估算重症监护室住院患者住院时间的生存模型,展示了所建议程序的实用性。Python包PyDTS可用于将建议的方法与其他功能一起应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Discrete-time competing-risks regression with or without penalization.

Many studies employ the analysis of time-to-event data that incorporates competing risks and right censoring. Most methods and software packages are geared towards analyzing data that comes from a continuous failure time distribution. However, failure-time data may sometimes be discrete either because time is inherently discrete or due to imprecise measurement. This paper introduces a new estimation procedure for discrete-time survival analysis with competing events. The proposed approach offers a major key advantage over existing procedures and allows for straightforward integration and application of widely used regularized regression and screening-features methods. We illustrate the benefits of our proposed approach by a comprehensive simulation study. Additionally, we showcase the utility of the proposed procedure by estimating a survival model for the length of stay of patients hospitalized in the intensive care unit, considering 3 competing events: discharge to home, transfer to another medical facility, and in-hospital death. A Python package, PyDTS, is available for applying the proposed method with additional features.

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来源期刊
Biometrics
Biometrics 生物-生物学
CiteScore
2.70
自引率
5.30%
发文量
178
审稿时长
4-8 weeks
期刊介绍: The International Biometric Society is an international society promoting the development and application of statistical and mathematical theory and methods in the biosciences, including agriculture, biomedical science and public health, ecology, environmental sciences, forestry, and allied disciplines. The Society welcomes as members statisticians, mathematicians, biological scientists, and others devoted to interdisciplinary efforts in advancing the collection and interpretation of information in the biosciences. The Society sponsors the biennial International Biometric Conference, held in sites throughout the world; through its National Groups and Regions, it also Society sponsors regional and local meetings.
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