黄斑脊:患病率及相关因素——北京眼科研究。

IF 3 3区 医学 Q1 OPHTHALMOLOGY
Jost B Jonas, Songhomitra Panda-Jonas, Jie Xu, Wen Bin Wei, Ya Xing Wang
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引用次数: 0

摘要

目的:在以人群为基础的研究样本中探讨黄斑嵴的患病率及其相关因素。方法:从以人群为基础的北京眼科研究(n = 3468)的参与者中,我们纳入了所有眼轴长度≥25 mm的眼睛和随机抽取的剩余近视眼睛样本。使用光学相干层析成像,我们评估了黄斑脊的患病率和高度,定义为中央凹区域在一条子午线上的高度。结果:366只研究眼中,50只(13.7%);95% CI: 10.1, 17.2)显示黄斑脊。黄斑脊患病率从轴向长度≤23 mm组的0/78(0%)增加到轴向长度为26-26.99 mm、27-27.99 mm和≥28 mm组的18/71(25.4%)、7/27(25.9%)和15/29(51.7%)。高黄斑嵴患病率(多变量分析)与较长的轴长相关(OR: 1.79;95% ci: 1.48, 2.16;结论:黄斑脊在近视眼中较为常见,黄斑脊的患病率和高度随眼轴长和年龄的增长呈曲线增长。它们与角膜散光或最佳矫正视力无显著相关性。这可能是由于眼底中周缘布氏膜轴向伸长相关扩大的平面间不对称所致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Macular ridges: Prevalence and associated factors-The Beijing Eye Study.

Purpose: To explore the prevalence and associated factors of macular ridges in a population-based study sample.

Methods: From the participants of the population-based Beijing Eye Study (n = 3468), we included all eyes with an axial length of ≥25 mm and a randomized sample of the remaining myopic eyes. Using optical coherence tomographic images, we assessed the prevalence and height of macular ridges, defined as an elevation of the foveal region in one meridian.

Results: Among 366 study eyes, 50 (13.7%; 95% CI: 10.1, 17.2) showed macular ridges. Macular ridge prevalence increased from 0/78 (0%) in the group with an axial length of ≤23 mm to 18/71 (25.4%), 7/27 (25.9%) and 15/29 (51.7%) in axial length groups of 26-26.99 mm, 27-27.99 mm and ≥28 mm, respectively. Higher macular ridge prevalence was associated (multivariable analysis) with longer axial length (OR: 1.79; 95% CI: 1.48, 2.16; p < 0.001) and older age (OR: 1.08; 95% CI: 1.04, 1.12; p < 0.001). Macular ridge height (mean:128 ± 79 μm) increased with longer axial length (0.31; B: 7.84; 95% CI: 5.39, 10.3; p < 0.001) and older age (beta: 0.16; B: 0.88; 95% CI: 0.34, 1.42; p < 0.001). Macular ridge orientation was most often in the horizontal meridian (28/50 eyes; 56%), followed by the vertical meridian (9/50 eyes; 18%) and the 7 o'clock-to-1 o'clock meridian (8/50 eyes; 16%). It was not significantly (p = 0.17) associated with the axis of cylindrical corneal refractive error.

Conclusions: Macular ridges were relatively common in myopic eyes, with macular ridge prevalence and height increasing with longer axial length and older age in a curvilinear manner. They were not significantly associated with corneal astigmatism or best-corrected visual acuity. They may be explained by an inter-plane asymmetry in axial elongation-associated enlargement of Bruch's membrane in the fundus midperiphery.

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来源期刊
Acta Ophthalmologica
Acta Ophthalmologica 医学-眼科学
CiteScore
7.60
自引率
5.90%
发文量
433
审稿时长
6 months
期刊介绍: Acta Ophthalmologica is published on behalf of the Acta Ophthalmologica Scandinavica Foundation and is the official scientific publication of the following societies: The Danish Ophthalmological Society, The Finnish Ophthalmological Society, The Icelandic Ophthalmological Society, The Norwegian Ophthalmological Society and The Swedish Ophthalmological Society, and also the European Association for Vision and Eye Research (EVER). Acta Ophthalmologica publishes clinical and experimental original articles, reviews, editorials, educational photo essays (Diagnosis and Therapy in Ophthalmology), case reports and case series, letters to the editor and doctoral theses.
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