Rebecca E Harding, Tamsin Barton, Maeve Niepceron, Ella Harris, Emily Bennett, Emily Gent, Flora Fraser, Celia J A Morgan
{"title":"氯胺酮使用障碍的前景:患者经验和对当前治疗方案的看法。","authors":"Rebecca E Harding, Tamsin Barton, Maeve Niepceron, Ella Harris, Emily Bennett, Emily Gent, Flora Fraser, Celia J A Morgan","doi":"10.1111/add.70073","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>To report the symptoms and aetiology of ketamine use disorder (KUD), gauge the effectiveness of current treatment services and identify strategies to enhance patient access and outcomes.</p><p><strong>Design: </strong>Mixed-methods, cross-sectional questionnaire. Electronic survey from November 2023 to April 2024.</p><p><strong>Setting: </strong>Participants were recruited through snowball sampling, social media and referrals from UK addiction treatment services. The survey was open to international participants, with responses collected from the United Kingdom, United States, Canada, Europe and Australia.</p><p><strong>Participants/cases: </strong>A total of 274 individuals with self-identified KUD, including both treatment-seeking (40%) and non-treatment-seeking (60%) current or former ketamine users. Participants' ages ranged from 18 to 67 years old, with 47.7% identifying as male. Additionally, 58.8% reported a diagnosed mental health disorder. On average, participants consumed 2.0 g of ketamine per day, with treatment-seeking individuals reporting higher average use (M = 2.67 g) than non-treatment-seeking users (M = 1.68 g) (P < 0.001).</p><p><strong>Measurements: </strong>Participants completed an online questionnaire addressing their attitudes toward ketamine and treatment services, including questions pertaining to their symptoms of problematic ketamine use, perceptions of education and awareness about KUD, opinions of existing treatment options, and facilitators for seeking treatment.</p><p><strong>Findings: </strong>The study identified various physical symptoms associated with KUD, with bladder problems (60%), nasal problems (60%) and 'K-cramps' (56%) being commonly reported among all users. In response to these symptoms, the majority (56%) did not seek treatment; among treatment-seeking users only 36% reported feeling satisfied with their care. Symptoms of abstinence syndrome were also identified, including cravings (71%), low mood (62%), anxiety (59%) and irritability (45%). Treatment-seeking participants reported that the services they used had little (31%) or some (31%) awareness of ketamine, were not tailored to ketamine use (43%) and were generally only somewhat effective (43%). Fifty-nine percent of participants reported that there was \"definitely not\" sufficient awareness in education and peer groups about the risks associated with ketamine use. When asked about the most important factors when choosing a treatment program, cost/affordability was the most cited for all participants.</p><p><strong>Conclusions: </strong>Ketamine use disorder (KUD) appears to be associated with a high prevalence of physical and psychological symptoms, including some specifically linked to abstinence. Despite this, most individuals with KUD do not seek treatment, and existing services are often perceived as ineffective.</p>","PeriodicalId":109,"journal":{"name":"Addiction","volume":" ","pages":""},"PeriodicalIF":5.2000,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The landscape of ketamine use disorder: Patient experiences and perspectives on current treatment options.\",\"authors\":\"Rebecca E Harding, Tamsin Barton, Maeve Niepceron, Ella Harris, Emily Bennett, Emily Gent, Flora Fraser, Celia J A Morgan\",\"doi\":\"10.1111/add.70073\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>To report the symptoms and aetiology of ketamine use disorder (KUD), gauge the effectiveness of current treatment services and identify strategies to enhance patient access and outcomes.</p><p><strong>Design: </strong>Mixed-methods, cross-sectional questionnaire. Electronic survey from November 2023 to April 2024.</p><p><strong>Setting: </strong>Participants were recruited through snowball sampling, social media and referrals from UK addiction treatment services. The survey was open to international participants, with responses collected from the United Kingdom, United States, Canada, Europe and Australia.</p><p><strong>Participants/cases: </strong>A total of 274 individuals with self-identified KUD, including both treatment-seeking (40%) and non-treatment-seeking (60%) current or former ketamine users. Participants' ages ranged from 18 to 67 years old, with 47.7% identifying as male. Additionally, 58.8% reported a diagnosed mental health disorder. On average, participants consumed 2.0 g of ketamine per day, with treatment-seeking individuals reporting higher average use (M = 2.67 g) than non-treatment-seeking users (M = 1.68 g) (P < 0.001).</p><p><strong>Measurements: </strong>Participants completed an online questionnaire addressing their attitudes toward ketamine and treatment services, including questions pertaining to their symptoms of problematic ketamine use, perceptions of education and awareness about KUD, opinions of existing treatment options, and facilitators for seeking treatment.</p><p><strong>Findings: </strong>The study identified various physical symptoms associated with KUD, with bladder problems (60%), nasal problems (60%) and 'K-cramps' (56%) being commonly reported among all users. In response to these symptoms, the majority (56%) did not seek treatment; among treatment-seeking users only 36% reported feeling satisfied with their care. Symptoms of abstinence syndrome were also identified, including cravings (71%), low mood (62%), anxiety (59%) and irritability (45%). Treatment-seeking participants reported that the services they used had little (31%) or some (31%) awareness of ketamine, were not tailored to ketamine use (43%) and were generally only somewhat effective (43%). Fifty-nine percent of participants reported that there was \\\"definitely not\\\" sufficient awareness in education and peer groups about the risks associated with ketamine use. When asked about the most important factors when choosing a treatment program, cost/affordability was the most cited for all participants.</p><p><strong>Conclusions: </strong>Ketamine use disorder (KUD) appears to be associated with a high prevalence of physical and psychological symptoms, including some specifically linked to abstinence. Despite this, most individuals with KUD do not seek treatment, and existing services are often perceived as ineffective.</p>\",\"PeriodicalId\":109,\"journal\":{\"name\":\"Addiction\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":5.2000,\"publicationDate\":\"2025-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Addiction\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/add.70073\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Addiction","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/add.70073","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
The landscape of ketamine use disorder: Patient experiences and perspectives on current treatment options.
Aims: To report the symptoms and aetiology of ketamine use disorder (KUD), gauge the effectiveness of current treatment services and identify strategies to enhance patient access and outcomes.
Design: Mixed-methods, cross-sectional questionnaire. Electronic survey from November 2023 to April 2024.
Setting: Participants were recruited through snowball sampling, social media and referrals from UK addiction treatment services. The survey was open to international participants, with responses collected from the United Kingdom, United States, Canada, Europe and Australia.
Participants/cases: A total of 274 individuals with self-identified KUD, including both treatment-seeking (40%) and non-treatment-seeking (60%) current or former ketamine users. Participants' ages ranged from 18 to 67 years old, with 47.7% identifying as male. Additionally, 58.8% reported a diagnosed mental health disorder. On average, participants consumed 2.0 g of ketamine per day, with treatment-seeking individuals reporting higher average use (M = 2.67 g) than non-treatment-seeking users (M = 1.68 g) (P < 0.001).
Measurements: Participants completed an online questionnaire addressing their attitudes toward ketamine and treatment services, including questions pertaining to their symptoms of problematic ketamine use, perceptions of education and awareness about KUD, opinions of existing treatment options, and facilitators for seeking treatment.
Findings: The study identified various physical symptoms associated with KUD, with bladder problems (60%), nasal problems (60%) and 'K-cramps' (56%) being commonly reported among all users. In response to these symptoms, the majority (56%) did not seek treatment; among treatment-seeking users only 36% reported feeling satisfied with their care. Symptoms of abstinence syndrome were also identified, including cravings (71%), low mood (62%), anxiety (59%) and irritability (45%). Treatment-seeking participants reported that the services they used had little (31%) or some (31%) awareness of ketamine, were not tailored to ketamine use (43%) and were generally only somewhat effective (43%). Fifty-nine percent of participants reported that there was "definitely not" sufficient awareness in education and peer groups about the risks associated with ketamine use. When asked about the most important factors when choosing a treatment program, cost/affordability was the most cited for all participants.
Conclusions: Ketamine use disorder (KUD) appears to be associated with a high prevalence of physical and psychological symptoms, including some specifically linked to abstinence. Despite this, most individuals with KUD do not seek treatment, and existing services are often perceived as ineffective.
期刊介绍:
Addiction publishes peer-reviewed research reports on pharmacological and behavioural addictions, bringing together research conducted within many different disciplines.
Its goal is to serve international and interdisciplinary scientific and clinical communication, to strengthen links between science and policy, and to stimulate and enhance the quality of debate. We seek submissions that are not only technically competent but are also original and contain information or ideas of fresh interest to our international readership. We seek to serve low- and middle-income (LAMI) countries as well as more economically developed countries.
Addiction’s scope spans human experimental, epidemiological, social science, historical, clinical and policy research relating to addiction, primarily but not exclusively in the areas of psychoactive substance use and/or gambling. In addition to original research, the journal features editorials, commentaries, reviews, letters, and book reviews.