通过分子内SN2反应合成双角鲨A和法根酮B的不同研究。

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-05-07 DOI:10.1039/D5OB00655D

Chen Guo, Mao-Mei Zhu, Si-Ji Ze Lang, Ya-Wen Wang, Jian Xiao and Yu Peng

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引用次数: 0

摘要

对双角鲨A和法基酮B的合成研究首次提出了不同的方法。这两种天然产物的[6-5-6]和[6-7-6]三环核心中的关键氧合五元或七元环可以由共同的高级中间体11通过区域选择性的分子内SN2反应构建。

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Divergent synthetic studies towards bisabosqual A and fargenone B via an intramolecular SN2 reaction†

A divergent approach has been developed towards the synthetic studies of bisabosqual A and fargenone B for the first time. The key oxygenated five- or seven-membered ring in [6–5–6] and [6–7–6] tricyclic cores of these two natural products could be constructed through a regioselective intramolecular S_N2 reaction from the common advanced intermediate 11.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.