脲基多组分反应合成二氢嘧啶类化合物。

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-04-26 DOI:10.1039/d5ob00180c

Anirban Mandal , Prasanjit Ghosh , Sajal Das

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引用次数: 0

摘要

多组分反应（mcr）已成为有机化学领域的有力工具，使复杂分子结构的快速高效组装成为可能。基于尿素的多组分反应因其多功能性和广泛的适用性而受到广泛关注。本文综述了近年来脲基mcr的研究进展，重点介绍了脲基mcr的合成途径和应用，揭示了其基本机理、反应条件和绿色可持续合成的潜力。

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Synthesis of dihydropyrimidinones via urea-based multicomponent reactions

Multicomponent reactions (MCRs) have emerged as powerful tools in organic chemistry, enabling the rapid and efficient assembly of complex molecular architectures. Urea-based multicomponent reactions have gained significant attention due to their versatility and broad applicability. In this review, we highlight recent developments in this area, with a focus on dihydropyrimidinones, and provide an in-depth analysis of the diverse synthetic pathways and applications of urea-based MCRs, shedding light on their fundamental mechanisms, reaction conditions, and potential for green and sustainable synthesis.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.