Joon Suk Bae, Young Hun Kang, Eun Soo Park, Seung Min Nam, Chang Yong Choi
{"title":"降钙素原作为压迫性损伤患者骨髓炎的诊断指标：一项回顾性研究。","authors":"Joon Suk Bae, Young Hun Kang, Eun Soo Park, Seung Min Nam, Chang Yong Choi","doi":"10.1097/ASW.0000000000000276","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To assess the diagnostic potential of procalcitonin in identifying osteomyelitis in patients with pressure injuries (PIs).</p><p><strong>Methods: </strong>The authors conducted a retrospective study of 21 patients with PIs from 2017 to 2022. Inflammatory markers (white blood cell count, erythrocyte sedimentation rate, C-reactive protein, procalcitonin) and radiologic images were analyzed to determine osteomyelitis presence. Patients were divided into osteomyelitis-positive and osteomyelitis-negative groups, with marker levels compared statistically.</p><p><strong>Results: </strong>Both C-reactive protein and procacitonin levels were significantly higher in the osteomyelitis group (Ps = .05). Elevated procalcitonin (>0.5) indicated a 10.67 times higher likelihood of osteomyelitis.</p><p><strong>Conclusions: </strong>Procalcitonin may serve as a valuable marker for diagnosing osteomyelitis in patients with PIs, aiding in early detection and treatment planning. Further research with larger cohorts is needed to confirm its diagnostic and monitoring potential.</p>","PeriodicalId":7489,"journal":{"name":"Advances in Skin & Wound Care","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Procalcitonin as a Diagnostic Marker for Osteomyelitis in Patients with Pressure Injuries: A Retrospective Study.\",\"authors\":\"Joon Suk Bae, Young Hun Kang, Eun Soo Park, Seung Min Nam, Chang Yong Choi\",\"doi\":\"10.1097/ASW.0000000000000276\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To assess the diagnostic potential of procalcitonin in identifying osteomyelitis in patients with pressure injuries (PIs).</p><p><strong>Methods: </strong>The authors conducted a retrospective study of 21 patients with PIs from 2017 to 2022. Inflammatory markers (white blood cell count, erythrocyte sedimentation rate, C-reactive protein, procalcitonin) and radiologic images were analyzed to determine osteomyelitis presence. Patients were divided into osteomyelitis-positive and osteomyelitis-negative groups, with marker levels compared statistically.</p><p><strong>Results: </strong>Both C-reactive protein and procacitonin levels were significantly higher in the osteomyelitis group (Ps = .05). Elevated procalcitonin (>0.5) indicated a 10.67 times higher likelihood of osteomyelitis.</p><p><strong>Conclusions: </strong>Procalcitonin may serve as a valuable marker for diagnosing osteomyelitis in patients with PIs, aiding in early detection and treatment planning. Further research with larger cohorts is needed to confirm its diagnostic and monitoring potential.</p>\",\"PeriodicalId\":7489,\"journal\":{\"name\":\"Advances in Skin & Wound Care\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-05-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Skin & Wound Care\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/ASW.0000000000000276\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Skin & Wound Care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/ASW.0000000000000276","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Procalcitonin as a Diagnostic Marker for Osteomyelitis in Patients with Pressure Injuries: A Retrospective Study.
Objective: To assess the diagnostic potential of procalcitonin in identifying osteomyelitis in patients with pressure injuries (PIs).
Methods: The authors conducted a retrospective study of 21 patients with PIs from 2017 to 2022. Inflammatory markers (white blood cell count, erythrocyte sedimentation rate, C-reactive protein, procalcitonin) and radiologic images were analyzed to determine osteomyelitis presence. Patients were divided into osteomyelitis-positive and osteomyelitis-negative groups, with marker levels compared statistically.
Results: Both C-reactive protein and procacitonin levels were significantly higher in the osteomyelitis group (Ps = .05). Elevated procalcitonin (>0.5) indicated a 10.67 times higher likelihood of osteomyelitis.
Conclusions: Procalcitonin may serve as a valuable marker for diagnosing osteomyelitis in patients with PIs, aiding in early detection and treatment planning. Further research with larger cohorts is needed to confirm its diagnostic and monitoring potential.
期刊介绍：
A peer-reviewed, multidisciplinary journal, Advances in Skin & Wound Care is highly regarded for its unique balance of cutting-edge original research and practical clinical management articles on wounds and other problems of skin integrity. Each issue features CME/CE for physicians and nurses, the first journal in the field to regularly offer continuing education for both disciplines.
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