从植物和微生物中增强色素生产:基因组编辑方法。

IF 2.6 4区 生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
3 Biotech Pub Date : 2025-05-01 Epub Date: 2025-04-16 DOI:10.1007/s13205-025-04290-w
P Harshini, Ressin Varghese, Kannan Pachamuthu, Siva Ramamoorthy
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引用次数: 0

摘要

众所周知,色素在植物和微生物的生长发育中起着至关重要的作用。此外,由于其巨大的颜色和治疗潜力,它们也是包括纺织、食品和制药在内的几个行业的必不可少的组成部分。传统上,色素是从植物资源中获得的,体外繁殖技术的出现促进了色素的大规模生产。然而,它不能满足蓬勃发展的需求,导致新的基因工程工具的结合。本文综述了各种基因工程技术在提高植物和微生物色素生产中的作用。它还批判性地分析了这些技术在增加色素生物合成方面的功效和瓶颈。此外,本文还讨论了利用微生物作为色素生物工厂以及基因组编辑技术增强色素合成的前景。现有技术的局限性强调了需要先进的基因组编辑策略来扩大色素的大规模生产,以满足不断增长的需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Enhanced pigment production from plants and microbes: a genome editing approach.

Pigments are known for their vital roles in the growth and development of plants and microbes. In addition, they are also an imperative component of several industries, including textiles, foods, and pharmaceuticals, owing to their immense colours and therapeutic potential. Conventionally, pigments are obtained from plant resources, and the advent of in-vitro propagation techniques boosted the massive production. However, it could not meet the booming demand, leading to the incorporation of new genetic engineering tools. This review focuses on the role of various genetic engineering techniques in enhancing pigment production in plants and microorganisms. It also critically analyzes the efficacy and bottlenecks of these techniques in augmenting pigment biosynthesis. Furthermore, the use of microbes as pigment biofactories and the prospects in the field of genome editing to augment pigment synthesis are discussed. The limitations in the existing techniques underline the need for advanced genome editing strategies to broaden the mass production of pigments to meet the surging needs.

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来源期刊
3 Biotech
3 Biotech Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)
CiteScore
6.00
自引率
0.00%
发文量
314
期刊介绍: 3 Biotech publishes the results of the latest research related to the study and application of biotechnology to: - Medicine and Biomedical Sciences - Agriculture - The Environment The focus on these three technology sectors recognizes that complete Biotechnology applications often require a combination of techniques. 3 Biotech not only presents the latest developments in biotechnology but also addresses the problems and benefits of integrating a variety of techniques for a particular application. 3 Biotech will appeal to scientists and engineers in both academia and industry focused on the safe and efficient application of Biotechnology to Medicine, Agriculture and the Environment.
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