铑催化的含拴链羰基的同丙烯醇异构化：1,6-二酮的途径。

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-05-14 DOI:10.1039/d5ob00473j

Shuang Peng, Tong Su, Xuan Yang, Jia-Jie Li, Jie Wan, Hai-Liang Ni, Peng Cao, Ping Hu, Bi-Qin Wang, Bin Chen

{"title":"铑催化的含拴链羰基的同丙烯醇异构化：1,6-二酮的途径。","authors":"Shuang Peng, Tong Su, Xuan Yang, Jia-Jie Li, Jie Wan, Hai-Liang Ni, Peng Cao, Ping Hu, Bi-Qin Wang, Bin Chen","doi":"10.1039/d5ob00473j","DOIUrl":null,"url":null,"abstract":"Herein, we report a rhodium-catalyzed isomerization of homoallylic alcohols with a tethered carbonyl group to synthesize structurally diverse unsymmetrical 1,6-diketones with atom, step, and redox economy. By introducing chiral ligands, good enantioselective isomerization products can be obtained. The utility of this reaction was also demonstrated with diverse transformations.","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rhodium-catalyzed isomerization of homoallylic alcohols with a tethered carbonyl group: pathway to 1,6-diketones.\",\"authors\":\"Shuang Peng, Tong Su, Xuan Yang, Jia-Jie Li, Jie Wan, Hai-Liang Ni, Peng Cao, Ping Hu, Bi-Qin Wang, Bin Chen\",\"doi\":\"10.1039/d5ob00473j\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Herein, we report a rhodium-catalyzed isomerization of homoallylic alcohols with a tethered carbonyl group to synthesize structurally diverse unsymmetrical 1,6-diketones with atom, step, and redox economy. By introducing chiral ligands, good enantioselective isomerization products can be obtained. The utility of this reaction was also demonstrated with diverse transformations.\",\"PeriodicalId\":96,\"journal\":{\"name\":\"Organic & Biomolecular Chemistry\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-05-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic & Biomolecular Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d5ob00473j\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5ob00473j","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}

引用次数: 0

摘要

在此，我们报道了铑催化的同丙烯醇与拴链羰基的异构化反应，以原子、步长和氧化还原经济的方式合成结构多样的不对称1,6-二酮。通过引入手性配体，可以得到良好的对映选择性异构化产物。该反应的效用也通过不同的转化得到了证明。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Rhodium-catalyzed isomerization of homoallylic alcohols with a tethered carbonyl group: pathway to 1,6-diketones.

Herein, we report a rhodium-catalyzed isomerization of homoallylic alcohols with a tethered carbonyl group to synthesize structurally diverse unsymmetrical 1,6-diketones with atom, step, and redox economy. By introducing chiral ligands, good enantioselective isomerization products can be obtained. The utility of this reaction was also demonstrated with diverse transformations.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.