在无症状的受试者中,仰卧休息45分钟可获得一致的基线腰椎间盘高度。

IF 3 2区 医学 Q3 ENGINEERING, BIOMEDICAL
Nicole E Zimmer, James A Coppock, Andrzej S Kosinski, Charles E Spritzer, Adam P Goode, Louis E DeFrate
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引用次数: 0

摘要

目的:椎间盘(IVD)高度随脊柱暴露于高负荷和低负荷时期而每日波动。因此,在研究IVD力学时,在测量体内IVD高度之前考虑加载历史是很重要的。然而,文献中关于低负荷下体内腰椎IVD高度恢复时间缺乏共识。因此,我们试图确定45分钟的仰卧休息时间是否能在一天中不同时间测量体内腰椎IVD高度的一致基线。方法:9名无症状的参与者在45分钟仰卧休息后接受磁共振(MR)成像,从一天的上午7:00开始,在另一天的中午(10:30 AM-12:30 PM)。人工分割MR图像,测量L1-L2至L5-S1 ivd的平均高度。三个磁共振扫描被分割成三份,以评估分割的可重复性。结果:计算了一天中不同时间的类内相关系数(ICC)和均方根误差(RMSE) (ICC: 0.96;RMSE: 0.08 mm)和分割重复性(ICC: 0.97;RMSE: 0.08 mm)。结论:ICCs具有良好的可靠性,rmse低于IVD高度的1%,表明45分钟仰卧休息时间为测量上午7:00至下午12:30之间的腰椎IVD高度提供了一致的基线。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Resting Supine for 45 Minutes Yields Consistent Baseline Lumbar Intervertebral Disc Height in Asymptomatic Participants.

Purpose: Intervertebral disc (IVD) height fluctuates diurnally as the spine is exposed to periods of high and low loading. Therefore, accounting for loading history prior to measuring in vivo IVD height is important when investigating IVD mechanics. However, there is a lack of consensus in the literature on in vivo lumbar IVD height recovery times under low loads. Therefore, we sought to determine whether a 45-minute supine rest period yields a consistent baseline for measuring in vivo lumbar IVD height across different times of day.

Methods: Nine asymptomatic participants underwent magnetic resonance (MR) imaging following a 45-minute supine rest, beginning at 7:00 AM on one visit day and mid-day (10:30 AM-12:30 PM) on a separate day. MR images were manually segmented, and the mean heights of the L1-L2 through L5-S1 IVDs were measured. Three MR scans were segmented in triplicate to evaluate segmentation repeatability.

Results: Intraclass correlation coefficients (ICCs) and root mean squared error (RMSE) were calculated for different times of day (ICC: 0.96; RMSE: 0.08 mm) and for segmentation repeatability (ICC: 0.97; RMSE: 0.08 mm).

Conclusion: ICCs indicated excellent reliability, and RMSEs were below 1% of IVD height, suggesting that a 45-minute supine rest period provides a consistent baseline for measuring lumbar IVD height between 7:00 AM and 12:30 PM.

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来源期刊
Annals of Biomedical Engineering
Annals of Biomedical Engineering 工程技术-工程:生物医学
CiteScore
7.50
自引率
15.80%
发文量
212
审稿时长
3 months
期刊介绍: Annals of Biomedical Engineering is an official journal of the Biomedical Engineering Society, publishing original articles in the major fields of bioengineering and biomedical engineering. The Annals is an interdisciplinary and international journal with the aim to highlight integrated approaches to the solutions of biological and biomedical problems.
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