Hugh Logan Ellis, Liam Dunnell, Ruth Eyres, Julie Whitney, Cara Jennings, Dan Wilson, Jane Tippett, Dan F Stein, James Teo, Zina Ibrahim, Kenneth Rockwood
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引用次数: 0
摘要
背景:英国急诊科(EDs)面临着巨大的压力,就诊人数增加,等待时间延长,影响了体弱的老年人。临床虚弱量表(CFS)已被用于评估ED患者的虚弱程度,但其作为筛查工具的可靠性和预测准确性仍存在争议。目的:评估急诊科CFS的使用和可变性及其与患者结局的关系,包括出院率、住院时间、再入院率和死亡率。方法:回顾性队列研究2017年至2021年英国伦敦两家医院急诊科的就诊率。数据包括CFS评分、人口统计学、临床观察和结果。采用比较统计、logistic回归、Cox比例风险模型和竞争风险回归检验CFS的预测效度。结果:在123 324例ED就诊的样本中,CFS评分与不良结局密切相关:例如,对于长期死亡率(n = 33 475,事件= 8871),CFS单点增加与死亡风险增加25%相关(95% CI 1.23-1.26)。CFS评分在评分者之间和每次访问之间差异显著,中位数差异为两个水平(四分位数范围1-3)。组内相关系数分析显示,CFS评分差异的33.1%可归因于患者间差异,15.4%可归因于评分间差异,51.5%的剩余方差来自急性疾病严重程度等非虚弱因素。结论:慢性疲劳综合症与ED患者的关键预后相关。评分间的变异性和潜在的混杂因素限制了其一致性。应探索提高CFS评分可靠性的自动化作为支持主动管理的手段。
What can we learn from 68 000 clinical frailty scale scores? Evaluating the utility of frailty assessment in emergency departments.
Background: Emergency departments (EDs) in England are under significant strain, with increasing attendances and extended wait times, affecting frail older adults. The clinical frailty scale (CFS) has been implemented as a tool to assess frailty in ED settings, but its reliability and predictive accuracy as a screening tool remain debated.
Objective: To evaluate the use and variability of the CFS in EDs and its association with patient outcomes, including discharge rates, length of stay, readmission and mortality.
Methods: A retrospective cohort study of ED attendances at two London (UK) hospitals from 2017 to 2021. Data included CFS scores, demographics, clinical observations and outcomes. Comparative statistics, logistic regression, Cox proportional hazards models and competing risk regression were applied to examine CFS predictive validity.
Results: In a sample of 123 324 ED visits, CFS scores strongly correlated with adverse outcomes: e.g. for long-term mortality (n = 33 475, events = 8871), each CFS single-point increase was associated with a 25% increase in mortality risk (95% CI 1.23-1.26). CFS scores varied significantly between raters and across visits, median difference two levels (interquartile range 1-3). Intraclass correlation coefficient analysis showed that 33.1% of CFS score differences was attributable to between-patient differences, 15.4% to inter-rater differences, with 51.5% residual variance from non-frailty factors, such as acute illness severity.
Conclusion: The CFS is associated with crucial patient outcomes in the ED. Inter-rater variability and potentially confounding factors can limit its consistency. Automation to enhance CFS score reliability should be explored as a means to support proactive management.
期刊介绍:
Age and Ageing is an international journal publishing refereed original articles and commissioned reviews on geriatric medicine and gerontology. Its range includes research on ageing and clinical, epidemiological, and psychological aspects of later life.