{"title":"冠状动脉搭桥术后：预后营养指数在决定死亡率中的作用。","authors":"Burak Toprak, Abdulkadir Bilgiç","doi":"10.14744/AnatolJCardiol.2025.5109","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The objective of this study was to evaluate the relationship between both preoperative and postoperative Prognostic Nutritional Index values and postoperative mortality in patients undergoing Coronary Artery Bypass Grafting surgery.</p><p><strong>Methods: </strong>This retrospective cohort study included 440 patients who underwent Coronary Artery Bypass Grafting between March 2021 and April 2023. Preoperative and postoperative Prognostic Nutritional Index values were calculated based on serum albumin concentration and peripheral blood lymphocyte count. The primary outcome was mortality, with statistical analyses performed to assess the association between Prognostic Nutritional Index values (preoperative and postoperative) and mortality using univariate and multivariate methods.</p><p><strong>Results: </strong>A significant correlation was found between low preoperative Prognostic Nutritional Index and increased postoperative mortality risk (P < .05). A 1-unit increase in preoperative Prognostic Nutritional Index was associated with a 5% reduction in mortality risk (Odds ratio [OR] = 0.95, P < .001, 95% CI: 0.96-0.98). Similarly, the postoperative Prognostic Nutritional Index was significantly associated with mortality, with a 1-unit increase in postoperative Prognostic Nutritional Index corresponding to a 6% reduction in mortality risk (OR = 0.94, P < .001, 95% CI: 0.92-0.96). Both preoperative and postoperative Prognostic Nutritional Index values independently predicted mortality risk, with postoperative Prognostic Nutritional Index showing a stronger association with mortality outcomes.</p><p><strong>Conclusions: </strong>The study demonstrates that both preoperative and postoperative Prognostic Nutritional Index values are critical predictors of mortality risk in Coronary Artery Bypass Grafting patients. Early assessment of the Prognostic Nutritional Index, both preoperatively and postoperatively, could enhance risk stratification and improve patient outcomes through timely interventions.</p>","PeriodicalId":7835,"journal":{"name":"Anatolian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231389/pdf/","citationCount":"0","resultStr":"{\"title\":\"Post-Coronary Artery Bypass: The Power of Prognostic Nutritional Index in Determining Mortality.\",\"authors\":\"Burak Toprak, Abdulkadir Bilgiç\",\"doi\":\"10.14744/AnatolJCardiol.2025.5109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The objective of this study was to evaluate the relationship between both preoperative and postoperative Prognostic Nutritional Index values and postoperative mortality in patients undergoing Coronary Artery Bypass Grafting surgery.</p><p><strong>Methods: </strong>This retrospective cohort study included 440 patients who underwent Coronary Artery Bypass Grafting between March 2021 and April 2023. Preoperative and postoperative Prognostic Nutritional Index values were calculated based on serum albumin concentration and peripheral blood lymphocyte count. The primary outcome was mortality, with statistical analyses performed to assess the association between Prognostic Nutritional Index values (preoperative and postoperative) and mortality using univariate and multivariate methods.</p><p><strong>Results: </strong>A significant correlation was found between low preoperative Prognostic Nutritional Index and increased postoperative mortality risk (P < .05). A 1-unit increase in preoperative Prognostic Nutritional Index was associated with a 5% reduction in mortality risk (Odds ratio [OR] = 0.95, P < .001, 95% CI: 0.96-0.98). Similarly, the postoperative Prognostic Nutritional Index was significantly associated with mortality, with a 1-unit increase in postoperative Prognostic Nutritional Index corresponding to a 6% reduction in mortality risk (OR = 0.94, P < .001, 95% CI: 0.92-0.96). Both preoperative and postoperative Prognostic Nutritional Index values independently predicted mortality risk, with postoperative Prognostic Nutritional Index showing a stronger association with mortality outcomes.</p><p><strong>Conclusions: </strong>The study demonstrates that both preoperative and postoperative Prognostic Nutritional Index values are critical predictors of mortality risk in Coronary Artery Bypass Grafting patients. Early assessment of the Prognostic Nutritional Index, both preoperatively and postoperatively, could enhance risk stratification and improve patient outcomes through timely interventions.</p>\",\"PeriodicalId\":7835,\"journal\":{\"name\":\"Anatolian Journal of Cardiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-04-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231389/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anatolian Journal of Cardiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.14744/AnatolJCardiol.2025.5109\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anatolian Journal of Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.14744/AnatolJCardiol.2025.5109","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
背景：本研究的目的是评估冠状动脉搭桥术患者术前和术后预后营养指数值与术后死亡率之间的关系。方法：这项回顾性队列研究包括440例在2021年3月至2023年4月期间接受冠状动脉搭桥术的患者。根据血清白蛋白浓度和外周血淋巴细胞计数计算术前和术后预后营养指数值。主要结局是死亡率，采用单变量和多变量方法进行统计分析，评估预后营养指数值（术前和术后）与死亡率之间的关系。结果：术前预后营养指数低与术后死亡风险增高有显著相关性（P < 0.05）。术前预后营养指数增加1个单位与死亡风险降低5%相关（优势比[OR] = 0.95, P < 0.001, 95% CI: 0.96-0.98）。同样，术后预后营养指数与死亡率显著相关，术后预后营养指数每增加1个单位，死亡风险降低6% （OR = 0.94, P < 0.001, 95% CI: 0.92-0.96）。术前和术后预后营养指数值均可独立预测死亡风险，其中术后预后营养指数与死亡结果的相关性更强。结论：本研究表明，术前和术后预后营养指数值是冠状动脉搭桥术患者死亡风险的重要预测指标。术前和术后早期评估预后营养指数，可通过及时干预加强风险分层，改善患者预后。
Post-Coronary Artery Bypass: The Power of Prognostic Nutritional Index in Determining Mortality.
Background: The objective of this study was to evaluate the relationship between both preoperative and postoperative Prognostic Nutritional Index values and postoperative mortality in patients undergoing Coronary Artery Bypass Grafting surgery.
Methods: This retrospective cohort study included 440 patients who underwent Coronary Artery Bypass Grafting between March 2021 and April 2023. Preoperative and postoperative Prognostic Nutritional Index values were calculated based on serum albumin concentration and peripheral blood lymphocyte count. The primary outcome was mortality, with statistical analyses performed to assess the association between Prognostic Nutritional Index values (preoperative and postoperative) and mortality using univariate and multivariate methods.
Results: A significant correlation was found between low preoperative Prognostic Nutritional Index and increased postoperative mortality risk (P < .05). A 1-unit increase in preoperative Prognostic Nutritional Index was associated with a 5% reduction in mortality risk (Odds ratio [OR] = 0.95, P < .001, 95% CI: 0.96-0.98). Similarly, the postoperative Prognostic Nutritional Index was significantly associated with mortality, with a 1-unit increase in postoperative Prognostic Nutritional Index corresponding to a 6% reduction in mortality risk (OR = 0.94, P < .001, 95% CI: 0.92-0.96). Both preoperative and postoperative Prognostic Nutritional Index values independently predicted mortality risk, with postoperative Prognostic Nutritional Index showing a stronger association with mortality outcomes.
Conclusions: The study demonstrates that both preoperative and postoperative Prognostic Nutritional Index values are critical predictors of mortality risk in Coronary Artery Bypass Grafting patients. Early assessment of the Prognostic Nutritional Index, both preoperatively and postoperatively, could enhance risk stratification and improve patient outcomes through timely interventions.
期刊介绍：
The Anatolian Journal of Cardiology is an international monthly periodical on cardiology published on independent, unbiased, double-blinded and peer-review principles. The journal’s publication language is English.
The Anatolian Journal of Cardiology aims to publish qualified and original clinical, experimental and basic research on cardiology at the international level. The journal’s scope also covers editorial comments, reviews of innovations in medical education and practice, case reports, original images, scientific letters, educational articles, letters to the editor, articles on publication ethics, diagnostic puzzles, and issues in social cardiology.
The target readership includes academic members, specialists, residents, and general practitioners working in the fields of adult cardiology, pediatric cardiology, cardiovascular surgery and internal medicine.
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