天然深共晶溶剂萃取白桑根皮桑苷A的研究。

IF 4.3 3区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
ACS Omega Pub Date : 2025-04-21 eCollection Date: 2025-05-06 DOI:10.1021/acsomega.4c08800
Zhiyang Chen, Zhengyou He, Jialan Qin
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引用次数: 0

摘要

本研究建立了一种基于天然深共晶溶剂(NADESs)的超声波提取桑葚苷A的方法。设计了24种不同配方的天然深共晶溶剂(NADESs),以桑椹苷A含量为唯一评价指标,采用高效液相色谱法(HPLC)进行检测。结果表明,苹果酸:葡萄糖(1:3)的提取工艺中桑葚苷A含量最高,为0.06%,提取特异性良好。此外,还对影响NADES提取物的水分含量、提取温度、提取时间、料液比等参数进行了优化,并对NADES提取物的抗氧化活性进行了测试。最后,采用半动态吸附的方法对桑葚苷A在多孔聚合物珠上进行进一步细分离,在NADES萃取条件下得到纯度为82.9%的桑葚苷A精制产物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Natural Deep Eutectic Solvents for the Extraction of Mulberroside A from White Mulberry Root Bark.

Natural Deep Eutectic Solvents for the Extraction of Mulberroside A from White Mulberry Root Bark.

Natural Deep Eutectic Solvents for the Extraction of Mulberroside A from White Mulberry Root Bark.

Natural Deep Eutectic Solvents for the Extraction of Mulberroside A from White Mulberry Root Bark.

In this study, an ultrasonic extraction method of mulberroside A from Morus alba L. based on natural deep eutectic solvents (NADESs) was developed. A total of 24 natural deep eutectic solvents (NADESs) with different formulations were designed to extract M. alba L. powder, and high-performance liquid chromatography (HPLC) was used as the detection method, with the content of mulberroside A as the only evaluation index. The results showed that malic acid:glucose (1:3) contained the highest mulberroside A content of 0.06% with excellent extraction specificity. In addition, the parameters such as water content, extraction temperature, extraction time, and feed/liquid ratio, which have a great influence on NADESs, were optimized, and the antioxidant activity of NADES extracts was tested. Finally, further fine separation of mulberroside A by semidynamic adsorption on porous polymer beads yielded a refined product of mulberroside A under NADES extraction conditions with a purity of 82.9%.

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来源期刊
ACS Omega
ACS Omega Chemical Engineering-General Chemical Engineering
CiteScore
6.60
自引率
4.90%
发文量
3945
审稿时长
2.4 months
期刊介绍: ACS Omega is an open-access global publication for scientific articles that describe new findings in chemistry and interfacing areas of science, without any perceived evaluation of immediate impact.
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