上皮细胞对基质粘弹性的机械反应和微模黏弹性水凝胶的约束（ei . Sci. 18/2025）

IF 14.1 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-05-15 DOI:10.1002/advs.202570135

Giuseppe Ciccone, Mariana Azevedo Gonzalez-Oliva, Marie Versaevel, Marco Cantini, Massimo Vassalli, Manuel Salmeron-Sanchez, Sylvain Gabriele

{"title":"上皮细胞对基质粘弹性的机械反应和微模黏弹性水凝胶的约束（ei . Sci. 18/2025）","authors":"Giuseppe Ciccone, Mariana Azevedo Gonzalez-Oliva, Marie Versaevel, Marco Cantini, Massimo Vassalli, Manuel Salmeron-Sanchez, Sylvain Gabriele","doi":"10.1002/advs.202570135","DOIUrl":null,"url":null,"abstract":"<p><b>Micropatterned Viscoelastic Hydrogels</b></p><p>Mountains, representing elastic solids, and rivers, representing viscous fluids, illustrate the concept of viscoelasticity. Cell-like kayaks navigate narrow rivers on a hydrogel-like terrain, evoking confinement within viscoelastic environments. This image offers a glimpse into the study described in article number 2408635 where Manuel Salmeron-Sanchez, Sylvain Gabriele, and workers developed micropatterned viscoelastic hydrogels with narrow adhesive protein tracks to investigate how extracellular matrix viscoelasticity and spatial confinement regulate epithelial cell mechanobiology.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"12 18","pages":""},"PeriodicalIF":14.1000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/advs.202570135","citationCount":"0","resultStr":"{\"title\":\"Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels (Adv. Sci. 18/2025)\",\"authors\":\"Giuseppe Ciccone, Mariana Azevedo Gonzalez-Oliva, Marie Versaevel, Marco Cantini, Massimo Vassalli, Manuel Salmeron-Sanchez, Sylvain Gabriele\",\"doi\":\"10.1002/advs.202570135\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Micropatterned Viscoelastic Hydrogels</b></p><p>Mountains, representing elastic solids, and rivers, representing viscous fluids, illustrate the concept of viscoelasticity. Cell-like kayaks navigate narrow rivers on a hydrogel-like terrain, evoking confinement within viscoelastic environments. This image offers a glimpse into the study described in article number 2408635 where Manuel Salmeron-Sanchez, Sylvain Gabriele, and workers developed micropatterned viscoelastic hydrogels with narrow adhesive protein tracks to investigate how extracellular matrix viscoelasticity and spatial confinement regulate epithelial cell mechanobiology.\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":117,\"journal\":{\"name\":\"Advanced Science\",\"volume\":\"12 18\",\"pages\":\"\"},\"PeriodicalIF\":14.1000,\"publicationDate\":\"2025-05-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/advs.202570135\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Science\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202570135\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Science","FirstCategoryId":"88","ListUrlMain":"https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202570135","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

摘要

代表弹性固体的山和代表粘性流体的河说明了粘弹性的概念。细胞状的皮艇在水凝胶状的地形上航行，在粘弹性环境中唤起限制。该图像提供了对文章编号2408635中描述的研究的一瞥，Manuel Salmeron-Sanchez， Sylvain Gabriele和工作人员开发了具有狭窄粘附蛋白轨迹的微图案粘弹性水凝胶，以研究细胞外基质粘弹性和空间限制如何调节上皮细胞的力学生物学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels (Adv. Sci. 18/2025)

查看原文本刊更多论文

Epithelial Cell Mechanoresponse to Matrix Viscoelasticity and Confinement Within Micropatterned Viscoelastic Hydrogels (Adv. Sci. 18/2025)

Micropatterned Viscoelastic Hydrogels

Mountains, representing elastic solids, and rivers, representing viscous fluids, illustrate the concept of viscoelasticity. Cell-like kayaks navigate narrow rivers on a hydrogel-like terrain, evoking confinement within viscoelastic environments. This image offers a glimpse into the study described in article number 2408635 where Manuel Salmeron-Sanchez, Sylvain Gabriele, and workers developed micropatterned viscoelastic hydrogels with narrow adhesive protein tracks to investigate how extracellular matrix viscoelasticity and spatial confinement regulate epithelial cell mechanobiology.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.