Margaret T. Berrigan MD, MS , Brendin R. Beaulieu-Jones MD, MBA, MBI , Jayson S. Marwaha MD, MBI , Stephen R. Odom MD, FACS , Alok Gupta MD, FACS , Charles S. Parsons MD, FACS , Anupamaa J. Seshadri MD, FACS , Charles H. Cook MD, FACS , Gabriel A. Brat MD, MPH, FACS
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We sought to combine ASA PS class with surgeon-generated risk estimates to create an easily deployed and accurate postsurgical risk stratification tool.</div></div><div><h3>Methods</h3><div>Surgeons at one academic center were surveyed before surgery to evaluate perceived risk of postsurgery complications. ASA PS class, presurgery clinical features, and clinical postsurgery outcomes were abstracted from an institutional database and the electronic health record. Binomial regression models predicting overall 30-d morbidity were trained using presurgery clinical features, ASA PS class, and surgeon risk estimates, alone and in combination.</div></div><div><h3>Results</h3><div>Surgeon risk estimates were collected from 11 surgeons for 286 patients undergoing 68 procedure types. One hundred seventy-five (61.89%) patients had ASA PS class 3 or higher. One hundred twenty (41.96%) patients were estimated to be at higher than average risk before surgery. The overall complication rate was 27.27%. ASA PS class and surgeon risk estimates predicted surgery complication with area under the receiver operating characteristic curve (AUC) 0.79 (95% confidence interval [CI] 0.71-0.86) and AUC 0.71 (95% CI 0.63-0.78), respectively. Combining ASA PS class and the surgeon risk estimate resulted in model discrimination (AUC 0.84, 95% CI 0.78-0.89) similar to that of a clinical data–based model (AUC 0.84, 95% CI 0.78-0.88). Subgroup analysis showed that attending surgeons are better able to predict postsurgery complications than senior trainees; risk estimates from both groups were improved by combination with the ASA PS class.</div></div><div><h3>Conclusions</h3><div>ASA PS class and surgeon risk estimates are independently predictive of overall 30-d morbidity. Taken together, these assessments resulted in improved anticipation of postsurgery complications with model discrimination on par with a traditional clinical data–based model. Judgment-derived assessments alone can be used to accurately predict a patient's postsurgery risk. Future research should identify scenarios where clinician judgment is especially valuable for postsurgery risk stratification and how to best integrate clinician judgment with risk stratification systems to encourage routine use of these tools and promote optimal postsurgery management.</div></div>","PeriodicalId":17030,"journal":{"name":"Journal of Surgical Research","volume":"310 ","pages":"Pages 323-330"},"PeriodicalIF":1.8000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Leveraging American Society of Anesthesiologists Physical Status Classification and Surgeon Risk Estimates to Stratify Surgical Risk: A Prospective Observational Study\",\"authors\":\"Margaret T. Berrigan MD, MS , Brendin R. Beaulieu-Jones MD, MBA, MBI , Jayson S. Marwaha MD, MBI , Stephen R. Odom MD, FACS , Alok Gupta MD, FACS , Charles S. Parsons MD, FACS , Anupamaa J. Seshadri MD, FACS , Charles H. Cook MD, FACS , Gabriel A. Brat MD, MPH, FACS\",\"doi\":\"10.1016/j.jss.2025.03.067\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>The American Society of Anesthesiologists Physical Status Classification (ASA PS class) is generated by the anesthesiologist before surgery. It is correlated with postoperative complications but does not integrate surgery-specific considerations or intraoperative events. We sought to combine ASA PS class with surgeon-generated risk estimates to create an easily deployed and accurate postsurgical risk stratification tool.</div></div><div><h3>Methods</h3><div>Surgeons at one academic center were surveyed before surgery to evaluate perceived risk of postsurgery complications. ASA PS class, presurgery clinical features, and clinical postsurgery outcomes were abstracted from an institutional database and the electronic health record. Binomial regression models predicting overall 30-d morbidity were trained using presurgery clinical features, ASA PS class, and surgeon risk estimates, alone and in combination.</div></div><div><h3>Results</h3><div>Surgeon risk estimates were collected from 11 surgeons for 286 patients undergoing 68 procedure types. One hundred seventy-five (61.89%) patients had ASA PS class 3 or higher. One hundred twenty (41.96%) patients were estimated to be at higher than average risk before surgery. The overall complication rate was 27.27%. ASA PS class and surgeon risk estimates predicted surgery complication with area under the receiver operating characteristic curve (AUC) 0.79 (95% confidence interval [CI] 0.71-0.86) and AUC 0.71 (95% CI 0.63-0.78), respectively. Combining ASA PS class and the surgeon risk estimate resulted in model discrimination (AUC 0.84, 95% CI 0.78-0.89) similar to that of a clinical data–based model (AUC 0.84, 95% CI 0.78-0.88). Subgroup analysis showed that attending surgeons are better able to predict postsurgery complications than senior trainees; risk estimates from both groups were improved by combination with the ASA PS class.</div></div><div><h3>Conclusions</h3><div>ASA PS class and surgeon risk estimates are independently predictive of overall 30-d morbidity. Taken together, these assessments resulted in improved anticipation of postsurgery complications with model discrimination on par with a traditional clinical data–based model. Judgment-derived assessments alone can be used to accurately predict a patient's postsurgery risk. 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引用次数: 0
摘要
美国麻醉医师协会身体状态分类(ASA PS类)是由麻醉医师在手术前生成的。它与术后并发症相关,但不包括手术特异性考虑因素或术中事件。我们试图将ASA PS分级与外科医生产生的风险评估相结合,以创建一个易于部署和准确的术后风险分层工具。方法对某学术中心的外科医生进行术前调查,评估术后并发症的感知风险。ASA PS等级、手术前临床特征和临床术后结果从机构数据库和电子健康记录中提取。预测总体30天发病率的二项回归模型使用手术临床特征、ASA PS等级和外科医生风险评估单独或联合进行训练。结果收集了11位外科医生对286例患者68种手术类型的风险评估。175例(61.89%)患者为ASA PS 3级或以上。120例(41.96%)患者术前风险高于平均水平。总并发症发生率为27.27%。ASA PS分级和外科医生风险估计预测手术并发症的受者操作特征曲线下面积(AUC)分别为0.79(95%可信区间[CI] 0.71-0.86)和0.71 (95% CI 0.63-0.78)。ASA PS等级和外科医生风险估计相结合导致模型歧视(AUC 0.84, 95% CI 0.78-0.89)与基于临床数据的模型(AUC 0.84, 95% CI 0.78-0.88)相似。亚组分析显示,主治医师比高级实习生更能预测术后并发症;与ASA PS分级相结合,两组的风险估计值均有所提高。结论sasa PS分级和外科医生风险评估可独立预测30 d总发病率。综上所述,这些评估与传统的基于临床数据的模型相比,提高了对术后并发症的预测。判断性评估可用于准确预测患者术后风险。未来的研究应该确定临床医生的判断对术后风险分层特别有价值的情况,以及如何最好地将临床医生的判断与风险分层系统结合起来,以鼓励常规使用这些工具,促进最佳的术后管理。
Leveraging American Society of Anesthesiologists Physical Status Classification and Surgeon Risk Estimates to Stratify Surgical Risk: A Prospective Observational Study
Introduction
The American Society of Anesthesiologists Physical Status Classification (ASA PS class) is generated by the anesthesiologist before surgery. It is correlated with postoperative complications but does not integrate surgery-specific considerations or intraoperative events. We sought to combine ASA PS class with surgeon-generated risk estimates to create an easily deployed and accurate postsurgical risk stratification tool.
Methods
Surgeons at one academic center were surveyed before surgery to evaluate perceived risk of postsurgery complications. ASA PS class, presurgery clinical features, and clinical postsurgery outcomes were abstracted from an institutional database and the electronic health record. Binomial regression models predicting overall 30-d morbidity were trained using presurgery clinical features, ASA PS class, and surgeon risk estimates, alone and in combination.
Results
Surgeon risk estimates were collected from 11 surgeons for 286 patients undergoing 68 procedure types. One hundred seventy-five (61.89%) patients had ASA PS class 3 or higher. One hundred twenty (41.96%) patients were estimated to be at higher than average risk before surgery. The overall complication rate was 27.27%. ASA PS class and surgeon risk estimates predicted surgery complication with area under the receiver operating characteristic curve (AUC) 0.79 (95% confidence interval [CI] 0.71-0.86) and AUC 0.71 (95% CI 0.63-0.78), respectively. Combining ASA PS class and the surgeon risk estimate resulted in model discrimination (AUC 0.84, 95% CI 0.78-0.89) similar to that of a clinical data–based model (AUC 0.84, 95% CI 0.78-0.88). Subgroup analysis showed that attending surgeons are better able to predict postsurgery complications than senior trainees; risk estimates from both groups were improved by combination with the ASA PS class.
Conclusions
ASA PS class and surgeon risk estimates are independently predictive of overall 30-d morbidity. Taken together, these assessments resulted in improved anticipation of postsurgery complications with model discrimination on par with a traditional clinical data–based model. Judgment-derived assessments alone can be used to accurately predict a patient's postsurgery risk. Future research should identify scenarios where clinician judgment is especially valuable for postsurgery risk stratification and how to best integrate clinician judgment with risk stratification systems to encourage routine use of these tools and promote optimal postsurgery management.
期刊介绍:
The Journal of Surgical Research: Clinical and Laboratory Investigation publishes original articles concerned with clinical and laboratory investigations relevant to surgical practice and teaching. The journal emphasizes reports of clinical investigations or fundamental research bearing directly on surgical management that will be of general interest to a broad range of surgeons and surgical researchers. The articles presented need not have been the products of surgeons or of surgical laboratories.
The Journal of Surgical Research also features review articles and special articles relating to educational, research, or social issues of interest to the academic surgical community.