分子内C-S环化法制备2-（n -芳香胺）苯并噻唑

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2025-04-29 DOI:10.1080/00397911.2025.2496696

Ratna Babu Gunturu (Investigation Methodology) , Prasanna Babu Racheeti (Investigation Methodology) , Usharani Mandapati (Formal analysis Methodology) , Ramana Tamminana (Supervision Writing – original draft Writing – review & editing) , Rameshraju Rudraraju (Supervision Writing – review & editing)

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引用次数: 0

摘要

在中等条件下，成功地进行了多种功能化n- 2-碘苯基- n1 -苯甲酰硫脲的铁催化C-S环化反应，得到了2-（n-芳香胺）苯并噻唑。承印物范围公差也有所扩大。对照实验证实了反应机理是通过分子内C-S交叉偶联反应进行的。

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Preparation of 2-(N-aroylamino)benzothiazoles via intramolecular C-S cyclization approach

The iron-catalyzed C-S cyclization of variety functional N-2-iodophenyl-N¹-benzoyl thioureas is successfully carried out to provide 2-(N-aroylamino) benzothiazoles in good to high yield under moderate conditions. Substrate scope tolerance has also been extended. Control experiments confirmed that the reaction mechanism proceeds through intra molecular C-S cross coupling reaction.

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.