碳氢化合物成膜剂和碳纳米材料增强防晒霜光防护的研究进展

IF 15.2 1区医学 Q1 PHARMACOLOGY & PHARMACY

Advanced drug delivery reviews Pub Date : 2025-05-13 DOI:10.1016/j.addr.2025.115607

Ajoa J. Addae , Jennifer Uyanga , Joey Chifamba , Paul S. Weiss

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引用次数: 0

摘要

最近在防晒配方的发展，已作出加强在皮肤表面形成的防晒膜。膜的形成对防晒霜特别有意义，因为溶解紫外线（UV）过滤器粘附在皮肤表面的能力，使它们有效地吸收紫外线，是防晒系数（SPF）值的重要决定因素。此外，在配方水平稳定防晒膜的方法是感兴趣的，因为防晒霜在皮肤样基材上的降解随着时间的推移。我们注意到，在确定防晒霜对人体皮肤的SPF值和光防护性能时，传统的基于溶剂的光谱测量防晒霜功效的方法只捕获了故事的一部分。在这篇前瞻性的综述中，我们重点介绍了使用碳氢化合物成膜剂和碳纳米材料增强防晒霜成膜的策略。我们讨论了在类皮肤基底上保持防晒膜附着力的挑战，概述了碳氢化合物成膜剂和碳纳米材料的特性，以改善光防护，并介绍了在配方层面分析防晒膜的最佳实践。总的来说，这篇综述为开发和评估防晒霜功效的防晒霜配方师和临床医生提供了相关的见解。

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Advances in enhancing photoprotection of sunscreens using hydrocarbon film formers and carbon nanomaterials

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Advances in enhancing photoprotection of sunscreens using hydrocarbon film formers and carbon nanomaterials

Recent developments in sunscreen formulations have been made to enhance sunscreen films formed on the surface of the skin. Film formation is of particular interest for sunscreens because the ability of solubilized ultraviolet (UV) filters to adhere to the skin’s surface in such a way that they efficiently absorb UV light is a significant determinant of sun protection factor (SPF) value. Additionally, methods of stabilizing sunscreen films at the formulation level are of interest due to the degradation of sunscreen on skin-like substrates overtime. We note that traditional solvent-based spectroscopic methods of measuring sunscreens’ efficacy capture only a portion of the story when it comes to determining SPF value and photoprotective properties of sunscreens on human skin. In this forward-looking review, we highlight strategies for enhancing film formation in sunscreens using hydrocarbon film formers and carbon nanomaterials. We discuss challenges of maintaining adhesion of sunscreen films on skin-like substrates, outline properties of hydrocarbon film formers and carbon nanomaterials for improving photoprotection, and present best practices for analyzing sunscreen films at the formulation level. Overall, this review provides insights relevant for sunscreen formulators and clinicians who develop and evaluate sunscreen efficacy.

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来源期刊

Advanced drug delivery reviews 医学-药学

CiteScore

28.10

自引率

5.00%

发文量

294

审稿时长

15.1 weeks

期刊介绍： The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery. In general, the Journal publishes review articles in a Theme Issue format. Each Theme Issue provides a comprehensive and critical examination of current and emerging research on the design and development of advanced drug and gene delivery systems and their application to experimental and clinical therapeutics. The goal is to illustrate the pivotal role of a multidisciplinary approach to modern drug delivery, encompassing the application of sound biological and physicochemical principles to the engineering of drug delivery systems to meet the therapeutic need at hand. Importantly the Editorial Team of ADDR asks that the authors effectively window the extensive volume of literature, pick the important contributions and explain their importance, produce a forward looking identification of the challenges facing the field and produce a Conclusions section with expert recommendations to address the issues.