利用铱AIEgens在水介质和活细胞中检测NAD(P)H的能力

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-04-16 DOI:10.1039/d5cc01124h

Ajay Gupta , Aryan Gautam , Smaranika Patra , Amit Kunwar , Pijus K. Sasmal

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引用次数: 0

摘要

设计了一种基于环金属化铱（III） AIEgens的荧光探针，用于快速、灵敏、特异地检测水中NAD(P)H。该探针已成功用于活癌细胞线粒体内NADH的生物成像，突出了其作为研究NADH相关细胞过程的有价值工具的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Harnessing the power of iridium AIEgens for NAD(P)H detection in aqueous medium and living cells†

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Harnessing the power of iridium AIEgens for NAD(P)H detection in aqueous medium and living cells†

A rationally designed luminescent probe based on cyclometalated iridium(iii) AIEgens was developed for the rapid, sensitive, and specific detection of NAD(P)H in aqueous media. This probe was successfully utilized for bioimaging of NADH within the mitochondria of living cancer cells, highlighting its potential as a valuable tool for investigating NADH-associated cellular processes.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.