柑桔精油芳香疗法对孕妇抑郁、压力和焦虑的影响一项随机对照临床试验

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-05-01 DOI:10.1016/j.tjog.2024.10.020

Maryam Moradi , Azin Niazi , Fereshteh Mohammadi Payandar , Jamshid Jamali , Noushin Arefadib

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引用次数: 0

摘要

许多女性在怀孕期间都会经历高压力、焦虑或抑郁。本研究的目的是确定柑橘精油芳香疗法对孕妇抑郁、压力和焦虑的影响。材料和方法这项随机临床试验包括68名孕妇，她们被随机分配到干预组，在干预组她们接受五滴柑橘精油，而对照组她们接受无味的甜杏仁油，每天两次，持续一个月，以面罩的形式，通过正常呼吸吸入20分钟。抑郁、焦虑和压力量表21项（DASS-21）在干预前后进行。数据分析采用SPSS软件（version 24）进行。p值<；0.05被认为具有统计学意义。结果对照组平均胎龄为29.30±2.14周，干预组平均胎龄为28.43±1.95周（p = 0.089）。在双变量分析中，干预显著改善了所有抑郁、焦虑和压力得分。干预组抑郁评分显著低于安慰剂组（- 4.80±6.22比1.03±5.90）(p <；0.001)。同样，干预后焦虑评分降低（- 3.37±3.52 vs. 0.79±4.39）(p <；0.001)。与安慰剂组相比，干预组的压力评分改善更多（- 3.77±4.94比1.39±4.99），但差异无统计学意义（p = 0.166）。然而，一项更复杂的分析显示，干预对抑郁（p = 0.001）和焦虑(p <；0.001)，但对应力没有影响（p = 0.166）。结论枳实精油芳香疗法对减轻孕妇抑郁和焦虑是安全有效的。然而，需要进一步的研究来阐明它对减轻压力的影响。试验注册号irct20200512047414n1。

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The effect of aromatherapy with Citrus Aurantium essential oil on depression, stress and anxiety in pregnant women; a randomized controlled clinical trial

Objective

Many women experience high stress, anxiety or depression during pregnancy. The aim of this study was to determine the effect of aromatherapy with Citrus Aurantium essential oil on depression, stress and anxiety in pregnant women.

Materials and methods

This randomized clinical trial included 68 pregnant women who were randomly assigned to either the intervention group where they received five drops of Citrus Aurantium essential oil or the control group where they received odorless sweet almond oil, both twice a day for one month in the form of facemasks which they inhaled through normal breathing for 20 min. The Depression, Anxiety, and Stress Scale–21 Items (DASS-21) were administered pre-and post-intervention. Data analysis was performed within SPSS software (version 24). P-value<0.05 was considered statistically significant.

Results

The mean gestational age was 29.30 ± 2.14 weeks in the control group and 28.43 ± 1.95 weeks in the intervention group (p = 0.089). In bi-variable analysis, the intervention significantly improved all depression, anxiety and stress scores. Depression scores significantly decreased in the intervention group compared to the placebo group (−4.80 ± 6.22 vs. 1.03 ± 5.90) (p < 0.001). Similarly, anxiety scores were reduced after the intervention (−3.37 ± 3.52 vs. 0.79 ± 4.39) (p < 0.001). Although stress scores improved more in the intervention group compared to placebo group (−3.77 ± 4.94 vs. 1.39 ± 4.99), the difference was not statistically significant (p = 0.166). However, a more sophisticated analysis revealed that the intervention had a significant effect on depression (p = 0.001) and anxiety (p < 0.001) but not on stress (p = 0.166).

Conclusion

Aromatherapy with Citrus Aurantium essential oil is effective and safe in reducing depression and anxiety in pregnant women. However, further research is needed to clarify its impact on stress reduction.

Trial Registration Number

IRCT20200512047414N1.

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.