乌干达阿祖德马尼区接受治疗的南苏丹艾滋病毒难民的发病率和随访损失预测因素

IF 1.5 Q4 INFECTIOUS DISEASES
Christopher Nyolonga , Joshua Uchaki Ufoyrwoth , Trinity Wanok , David Komakech , Joseph Baruch Baluku , Felix Bongomin
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引用次数: 0

摘要

目的难民艾滋病护理面临重大挑战。我们确定了乌干达感染艾滋病毒的南苏丹难民中随访损失(LTFU)的发生率和预测因素。方法我们在乌干达亚祖玛尼区公共卫生机构进行了一项回顾性队列研究,涉及感染艾滋病毒的南苏丹难民。LTFU被定义为自研究开始以来,在他们的护理过程中连续缺失3个月或更长时间。采用Cox比例风险回归分析确定LTFU的独立预测因子,并以调整后的风险比(aHRs)和相应的95%置信区间(CIs)表示结果。结果我们纳入了449名参与者的数据,中位年龄为37岁(四分位数范围:30-43岁)。大多数是女性患者(75.5%,n = 339),接受卫生中心(HC) III的护理(87.3%,n = 392),基线为世界卫生组织1期(79.3%,n = 341),基线结核状态为阴性(89.1%,n = 302),抑制病毒载量(86.5%,n = 360),无合并发病(91%,n = 402)。总的来说,25例(5.6%)失去随访。与LTFU独立相关的因素是男性(aHR: 2.6, 95% CI: 1.1-6.1, P = 0.03)和接受IV型HC护理(aHR: 3.0, 95% CI: 1.0-8.8, P = 0.04)。结论南苏丹难民在乌干达感染艾滋病毒的人群中存在大量的tfu。常规使用患者地址定位表,提高丙型肝炎病毒治疗的质量,以及针对男性的外展和社区参与,可能会减少感染艾滋病毒的难民的LTFU。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence and predictors of loss to follow-up among South Sudanese refugees with HIV receiving care in Adjumani District, Uganda

Objectives

HIV care pose a significant challenge in refugee population. We determined the incidence and predictors of loss to follow-up (LTFU) among South Sudanese refugees with HIV in Uganda.

Methods

We conducted a retrospective cohort study in public health facilities in Adjumani District, Uganda, involving South Sudanese refugees with HIV. LTFU was defined as missing 3 or more consecutive months at any point in their care since the start of the study period. A Cox proportional hazards regression analysis was fitted to determine independent predictors of LTFU and results are presented as adjusted hazard ratios (aHRs) with corresponding 95% confidence intervals (CIs).

Results

We included data of 449 participants, with a median age of 37 (interquartile range: 30-43) years. Most were female patients (75.5%, n = 339) receiving care from health center (HC) III (87.3%, n = 392), with baseline World Health Organization stage 1 (79.3%, n = 341), negative baseline tuberculosis status (89.1%, n = 302), and suppressed viral load (86.5%, n = 360) and had no co-morbidity (91%, n = 402). Overall, 25 (5.6%) were lost to follow-up. Factors independently associated with LTFU were being male (aHR: 2.6, 95% CI: 1.1-6.1, P = 0.03) and receiving care from HC IV (aHR: 3.0, 95% CI: 1.0-8.8, P = 0.04).

Conclusions

LTFU among South Sudanese refugees with HIV in Uganda is substantial. Routine use of patient address locator forms, and improved quality of HIV care at HC IV and men-targeted outreaches and community involvement may reduce LTFU among refugees living with HIV.
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来源期刊
IJID regions
IJID regions Infectious Diseases
CiteScore
1.60
自引率
0.00%
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64 days
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