Christopher Nyolonga , Joshua Uchaki Ufoyrwoth , Trinity Wanok , David Komakech , Joseph Baruch Baluku , Felix Bongomin
{"title":"乌干达阿祖德马尼区接受治疗的南苏丹艾滋病毒难民的发病率和随访损失预测因素","authors":"Christopher Nyolonga , Joshua Uchaki Ufoyrwoth , Trinity Wanok , David Komakech , Joseph Baruch Baluku , Felix Bongomin","doi":"10.1016/j.ijregi.2025.100653","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>HIV care pose a significant challenge in refugee population. We determined the incidence and predictors of loss to follow-up (LTFU) among South Sudanese refugees with HIV in Uganda.</div></div><div><h3>Methods</h3><div>We conducted a retrospective cohort study in public health facilities in Adjumani District, Uganda, involving South Sudanese refugees with HIV. LTFU was defined as missing 3 or more consecutive months at any point in their care since the start of the study period. A Cox proportional hazards regression analysis was fitted to determine independent predictors of LTFU and results are presented as adjusted hazard ratios (aHRs) with corresponding 95% confidence intervals (CIs).</div></div><div><h3>Results</h3><div>We included data of 449 participants, with a median age of 37 (interquartile range: 30-43) years. Most were female patients (75.5%, n = 339) receiving care from health center (HC) III (87.3%, n = 392), with baseline World Health Organization stage 1 (79.3%, n = 341), negative baseline tuberculosis status (89.1%, n = 302), and suppressed viral load (86.5%, n = 360) and had no co-morbidity (91%, n = 402). Overall, 25 (5.6%) were lost to follow-up. Factors independently associated with LTFU were being male (aHR: 2.6, 95% CI: 1.1-6.1, <em>P</em> = 0.03) and receiving care from HC IV (aHR: 3.0, 95% CI: 1.0-8.8, <em>P</em> = 0.04).</div></div><div><h3>Conclusions</h3><div>LTFU among South Sudanese refugees with HIV in Uganda is substantial. Routine use of patient address locator forms, and improved quality of HIV care at HC IV and men-targeted outreaches and community involvement may reduce LTFU among refugees living with HIV.</div></div>","PeriodicalId":73335,"journal":{"name":"IJID regions","volume":"15 ","pages":"Article 100653"},"PeriodicalIF":1.5000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incidence and predictors of loss to follow-up among South Sudanese refugees with HIV receiving care in Adjumani District, Uganda\",\"authors\":\"Christopher Nyolonga , Joshua Uchaki Ufoyrwoth , Trinity Wanok , David Komakech , Joseph Baruch Baluku , Felix Bongomin\",\"doi\":\"10.1016/j.ijregi.2025.100653\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>HIV care pose a significant challenge in refugee population. We determined the incidence and predictors of loss to follow-up (LTFU) among South Sudanese refugees with HIV in Uganda.</div></div><div><h3>Methods</h3><div>We conducted a retrospective cohort study in public health facilities in Adjumani District, Uganda, involving South Sudanese refugees with HIV. LTFU was defined as missing 3 or more consecutive months at any point in their care since the start of the study period. A Cox proportional hazards regression analysis was fitted to determine independent predictors of LTFU and results are presented as adjusted hazard ratios (aHRs) with corresponding 95% confidence intervals (CIs).</div></div><div><h3>Results</h3><div>We included data of 449 participants, with a median age of 37 (interquartile range: 30-43) years. Most were female patients (75.5%, n = 339) receiving care from health center (HC) III (87.3%, n = 392), with baseline World Health Organization stage 1 (79.3%, n = 341), negative baseline tuberculosis status (89.1%, n = 302), and suppressed viral load (86.5%, n = 360) and had no co-morbidity (91%, n = 402). Overall, 25 (5.6%) were lost to follow-up. Factors independently associated with LTFU were being male (aHR: 2.6, 95% CI: 1.1-6.1, <em>P</em> = 0.03) and receiving care from HC IV (aHR: 3.0, 95% CI: 1.0-8.8, <em>P</em> = 0.04).</div></div><div><h3>Conclusions</h3><div>LTFU among South Sudanese refugees with HIV in Uganda is substantial. Routine use of patient address locator forms, and improved quality of HIV care at HC IV and men-targeted outreaches and community involvement may reduce LTFU among refugees living with HIV.</div></div>\",\"PeriodicalId\":73335,\"journal\":{\"name\":\"IJID regions\",\"volume\":\"15 \",\"pages\":\"Article 100653\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-04-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IJID regions\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772707625000888\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IJID regions","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772707625000888","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Incidence and predictors of loss to follow-up among South Sudanese refugees with HIV receiving care in Adjumani District, Uganda
Objectives
HIV care pose a significant challenge in refugee population. We determined the incidence and predictors of loss to follow-up (LTFU) among South Sudanese refugees with HIV in Uganda.
Methods
We conducted a retrospective cohort study in public health facilities in Adjumani District, Uganda, involving South Sudanese refugees with HIV. LTFU was defined as missing 3 or more consecutive months at any point in their care since the start of the study period. A Cox proportional hazards regression analysis was fitted to determine independent predictors of LTFU and results are presented as adjusted hazard ratios (aHRs) with corresponding 95% confidence intervals (CIs).
Results
We included data of 449 participants, with a median age of 37 (interquartile range: 30-43) years. Most were female patients (75.5%, n = 339) receiving care from health center (HC) III (87.3%, n = 392), with baseline World Health Organization stage 1 (79.3%, n = 341), negative baseline tuberculosis status (89.1%, n = 302), and suppressed viral load (86.5%, n = 360) and had no co-morbidity (91%, n = 402). Overall, 25 (5.6%) were lost to follow-up. Factors independently associated with LTFU were being male (aHR: 2.6, 95% CI: 1.1-6.1, P = 0.03) and receiving care from HC IV (aHR: 3.0, 95% CI: 1.0-8.8, P = 0.04).
Conclusions
LTFU among South Sudanese refugees with HIV in Uganda is substantial. Routine use of patient address locator forms, and improved quality of HIV care at HC IV and men-targeted outreaches and community involvement may reduce LTFU among refugees living with HIV.