Nafiseh Samiseresht, Gabriela Figueroa Miranda, Ankita Das, Kevin Graef, Dirk Mayer, Martin Rabe
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Nano-Phase Separation and Analyte Binding in Aptasensors Investigated by Nano-IR Spectroscopy (Small 19/2025)
Biosensors
Understanding the nanostructure of biosensors is crucial for their tailored design. In article number 2409369, Martin Rabe and co-workers report a nanospectroscopic study of the fabrication and application of a DNA-aptamer biosensor designed for variant-specific sensing of the SARS-CoV-2 spike protein. Structural details such as chemical identification of nanophases and single-molecule detection of sensor-bound analyte are reported, advancing our understanding of the nanomorphology of these sensors.
期刊介绍:
Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments.
With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology.
Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.