Agnieszka Sobierajska-Rek , Wiktoria Wojnicz , Bartłomiej Zagrodny , Michał Ludwicki , Katarzyna Pytka , Joanna Jabłońska-Brudło
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The main goal of this study was to compare the upper limb movement strategy of patients with Duchenne muscular dystrophy and a healthy Control by assessing the contributions of chosen joint angles and contributions of muscles activity in the functional motions of activities of daily living.</div></div><div><h3>Method</h3><div>A novel score of kinematic and electromyographic patterns is proposed, and results are assessed for a whole trajectory of tested upper limb for five patients and a healthy Control. Contributions of four joint angles and four surface muscle activities are assessed for two relations – kinematic control (a relation between muscle activity and displacement of the wrist) and dynamic control (a relation between muscle activity and displacement of the center of mass of the upper limb).</div></div><div><h3>Findings</h3><div>In vertical motions, higher mobility in the shoulder and elbow was observed in patients with lower Brooke scores. In motions involving horizontal movement of a weight, the contribution of the elbow and the trapezius were higher in all patients vs the Control.</div></div><div><h3>Interpretation</h3><div>The proposed method revealed significant differences in muscle activity and upper limb movement patterns in patients with Duchenne muscular dystrophy compared with a healthy Control. Results of the assessment of contributions in kinematic control and dynamic control show individual movement strategies of patients with Duchenne muscular dystrophy.</div></div>","PeriodicalId":50992,"journal":{"name":"Clinical Biomechanics","volume":"126 ","pages":"Article 106542"},"PeriodicalIF":1.4000,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biomechanical analysis of upper limb of patients with Duchenne muscular dystrophy in chosen functional tasks: A multi-case study\",\"authors\":\"Agnieszka Sobierajska-Rek , Wiktoria Wojnicz , Bartłomiej Zagrodny , Michał Ludwicki , Katarzyna Pytka , Joanna Jabłońska-Brudło\",\"doi\":\"10.1016/j.clinbiomech.2025.106542\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The main symptom of Duchenne muscular dystrophy is progressive wasting of muscle tissue. Current research on motor measurements for these patients lacks assessments of the whole trajectories of the functional motions over time in clinical conditions. The main goal of this study was to compare the upper limb movement strategy of patients with Duchenne muscular dystrophy and a healthy Control by assessing the contributions of chosen joint angles and contributions of muscles activity in the functional motions of activities of daily living.</div></div><div><h3>Method</h3><div>A novel score of kinematic and electromyographic patterns is proposed, and results are assessed for a whole trajectory of tested upper limb for five patients and a healthy Control. Contributions of four joint angles and four surface muscle activities are assessed for two relations – kinematic control (a relation between muscle activity and displacement of the wrist) and dynamic control (a relation between muscle activity and displacement of the center of mass of the upper limb).</div></div><div><h3>Findings</h3><div>In vertical motions, higher mobility in the shoulder and elbow was observed in patients with lower Brooke scores. In motions involving horizontal movement of a weight, the contribution of the elbow and the trapezius were higher in all patients vs the Control.</div></div><div><h3>Interpretation</h3><div>The proposed method revealed significant differences in muscle activity and upper limb movement patterns in patients with Duchenne muscular dystrophy compared with a healthy Control. Results of the assessment of contributions in kinematic control and dynamic control show individual movement strategies of patients with Duchenne muscular dystrophy.</div></div>\",\"PeriodicalId\":50992,\"journal\":{\"name\":\"Clinical Biomechanics\",\"volume\":\"126 \",\"pages\":\"Article 106542\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-04-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Biomechanics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0268003325001159\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Biomechanics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0268003325001159","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Biomechanical analysis of upper limb of patients with Duchenne muscular dystrophy in chosen functional tasks: A multi-case study
Background
The main symptom of Duchenne muscular dystrophy is progressive wasting of muscle tissue. Current research on motor measurements for these patients lacks assessments of the whole trajectories of the functional motions over time in clinical conditions. The main goal of this study was to compare the upper limb movement strategy of patients with Duchenne muscular dystrophy and a healthy Control by assessing the contributions of chosen joint angles and contributions of muscles activity in the functional motions of activities of daily living.
Method
A novel score of kinematic and electromyographic patterns is proposed, and results are assessed for a whole trajectory of tested upper limb for five patients and a healthy Control. Contributions of four joint angles and four surface muscle activities are assessed for two relations – kinematic control (a relation between muscle activity and displacement of the wrist) and dynamic control (a relation between muscle activity and displacement of the center of mass of the upper limb).
Findings
In vertical motions, higher mobility in the shoulder and elbow was observed in patients with lower Brooke scores. In motions involving horizontal movement of a weight, the contribution of the elbow and the trapezius were higher in all patients vs the Control.
Interpretation
The proposed method revealed significant differences in muscle activity and upper limb movement patterns in patients with Duchenne muscular dystrophy compared with a healthy Control. Results of the assessment of contributions in kinematic control and dynamic control show individual movement strategies of patients with Duchenne muscular dystrophy.
期刊介绍:
Clinical Biomechanics is an international multidisciplinary journal of biomechanics with a focus on medical and clinical applications of new knowledge in the field.
The science of biomechanics helps explain the causes of cell, tissue, organ and body system disorders, and supports clinicians in the diagnosis, prognosis and evaluation of treatment methods and technologies. Clinical Biomechanics aims to strengthen the links between laboratory and clinic by publishing cutting-edge biomechanics research which helps to explain the causes of injury and disease, and which provides evidence contributing to improved clinical management.
A rigorous peer review system is employed and every attempt is made to process and publish top-quality papers promptly.
Clinical Biomechanics explores all facets of body system, organ, tissue and cell biomechanics, with an emphasis on medical and clinical applications of the basic science aspects. The role of basic science is therefore recognized in a medical or clinical context. The readership of the journal closely reflects its multi-disciplinary contents, being a balance of scientists, engineers and clinicians.
The contents are in the form of research papers, brief reports, review papers and correspondence, whilst special interest issues and supplements are published from time to time.
Disciplines covered include biomechanics and mechanobiology at all scales, bioengineering and use of tissue engineering and biomaterials for clinical applications, biophysics, as well as biomechanical aspects of medical robotics, ergonomics, physical and occupational therapeutics and rehabilitation.