用于电生理测量的刚性和软微电极

IF 4.7 3区工程技术 Q2 ENGINEERING, BIOMEDICAL

Current Opinion in Biomedical Engineering Pub Date : 2025-04-16 DOI:10.1016/j.cobme.2025.100591

Haoran Gong , Wenwen Weng , Shuhao Zhang , Zhigang Gao , Ning Hu

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引用次数: 0

摘要

电生理测量是检测电活动和分析细胞行为的一项重要技术。在各种电生理检测方法中，微电极阵列（MEAs）因其高效、准确地分析细胞和组织的电生理活动，近年来得到了广泛的研究。刚性mea因其方便性和可扩展性而受到青睐，广泛应用于药物选择、病理分析和光热研究。软mea具有灵活的几何形状和出色的生物相容性，更适合涉及三维类器官的应用。本文综述了近五年来刚性和软mea的最新进展，重点介绍了它们在心脏病学和神经科学中的应用。

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Rigid and soft microelectrodes for electrophysiology measurement

Electrophysiology measurement is a significant technique to detect electrical activities and analyze cell behaviors. Among various electrophysiological detection methods, microelectrode arrays (MEAs) have been widely investigated in recent years due to their high efficiency and accuracy in analyzing electrophysiological activities of cells and tissues. Rigid MEAs, favored for their convenience and scalability, are widely used in drug selection, pathological analysis, and photothermal research. Soft MEAs, with the flexible geometries and outstanding biocompatibility, are better suited for applications involving three-dimensional organoids. This review provides an overview of recent advances in rigid and soft MEAs over the past five years, focusing on their application in cardiology and neuroscience.

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来源期刊

Current Opinion in Biomedical Engineering Medicine-Medicine (miscellaneous)

CiteScore

8.60

自引率

2.60%

发文量