封面特征:Zn(II)-稳定自由基配体-活化自由基型C(sp3)-H -级联环化成咪唑吡啶

IF 3.9 2区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY
Subhasree Pal, Sucheta Mondal, Amit Kumar Guin, Nanda D. Paul
{"title":"封面特征:Zn(II)-稳定自由基配体-活化自由基型C(sp3)-H -级联环化成咪唑吡啶","authors":"Subhasree Pal,&nbsp;Sucheta Mondal,&nbsp;Amit Kumar Guin,&nbsp;Nanda D. Paul","doi":"10.1002/chem.202582604","DOIUrl":null,"url":null,"abstract":"<p><b>Imidazo[1,2-<i>a</i>]pyridines</b> act as the core unit for many commercially available drugs. Tandem cyclization between <i>N</i>-benzylpyridin-2-amines and terminal alkynes produces imidazo[1,2-<i>a</i>]pyridines when using a well-defined Zn<sup>II</sup> catalyst. Here, the girl and the boy represent the metal and the ligand centre, respectively. They work cooperatively to prepare delicious food symbolizing imidazo[1,2-<i>a</i>]pyridines. This depicts how metal–ligand cooperativity has a key role in this transformation, where all the redox events occur from the ligand, and the metal acts as a template. More information can be found in the Research Article by N. D. Paul and co-workers (DOI: 10.1002/chem.202500359).\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":"31 26","pages":""},"PeriodicalIF":3.9000,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/chem.202582604","citationCount":"0","resultStr":"{\"title\":\"Cover Feature: Zn(II)-Stabilized Radical Ligand Enabled Radical-Type C(sp3)-H Activation-Cascade Cyclization to Imidazopyridines\",\"authors\":\"Subhasree Pal,&nbsp;Sucheta Mondal,&nbsp;Amit Kumar Guin,&nbsp;Nanda D. Paul\",\"doi\":\"10.1002/chem.202582604\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><b>Imidazo[1,2-<i>a</i>]pyridines</b> act as the core unit for many commercially available drugs. Tandem cyclization between <i>N</i>-benzylpyridin-2-amines and terminal alkynes produces imidazo[1,2-<i>a</i>]pyridines when using a well-defined Zn<sup>II</sup> catalyst. Here, the girl and the boy represent the metal and the ligand centre, respectively. They work cooperatively to prepare delicious food symbolizing imidazo[1,2-<i>a</i>]pyridines. This depicts how metal–ligand cooperativity has a key role in this transformation, where all the redox events occur from the ligand, and the metal acts as a template. More information can be found in the Research Article by N. D. Paul and co-workers (DOI: 10.1002/chem.202500359).\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":144,\"journal\":{\"name\":\"Chemistry - A European Journal\",\"volume\":\"31 26\",\"pages\":\"\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/chem.202582604\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry - A European Journal\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/chem.202582604\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry - A European Journal","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/chem.202582604","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

摘要

咪唑[1,2-a]吡啶是许多市售药物的核心单位。n-苄基吡啶-2胺与末端炔之间的串联环化反应在定义良好的ni催化剂下生成咪唑[1,2-a]吡啶。在这里,女孩和男孩分别代表金属和配体中心。他们合作准备美味的食物象征咪唑[1,2-a]吡啶。这描述了金属-配体的协同性在这种转化中是如何起关键作用的,在这种转化中,所有的氧化还原事件都发生在配体上,金属充当模板。更多信息可以在n.d. Paul及其同事的研究文章中找到(DOI: 10.1002/chem.202500359)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cover Feature: Zn(II)-Stabilized Radical Ligand Enabled Radical-Type C(sp3)-H Activation-Cascade Cyclization to Imidazopyridines

Cover Feature: Zn(II)-Stabilized Radical Ligand Enabled Radical-Type C(sp3)-H Activation-Cascade Cyclization to Imidazopyridines

Imidazo[1,2-a]pyridines act as the core unit for many commercially available drugs. Tandem cyclization between N-benzylpyridin-2-amines and terminal alkynes produces imidazo[1,2-a]pyridines when using a well-defined ZnII catalyst. Here, the girl and the boy represent the metal and the ligand centre, respectively. They work cooperatively to prepare delicious food symbolizing imidazo[1,2-a]pyridines. This depicts how metal–ligand cooperativity has a key role in this transformation, where all the redox events occur from the ligand, and the metal acts as a template. More information can be found in the Research Article by N. D. Paul and co-workers (DOI: 10.1002/chem.202500359).

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Chemistry - A European Journal
Chemistry - A European Journal 化学-化学综合
CiteScore
7.90
自引率
4.70%
发文量
1808
审稿时长
1.8 months
期刊介绍: Chemistry—A European Journal is a truly international journal with top quality contributions (2018 ISI Impact Factor: 5.16). It publishes a wide range of outstanding Reviews, Minireviews, Concepts, Full Papers, and Communications from all areas of chemistry and related fields. Based in Europe Chemistry—A European Journal provides an excellent platform for increasing the visibility of European chemistry as well as for featuring the best research from authors from around the world. All manuscripts are peer-reviewed, and electronic processing ensures accurate reproduction of text and data, plus short publication times. The Concepts section provides nonspecialist readers with a useful conceptual guide to unfamiliar areas and experts with new angles on familiar problems. Chemistry—A European Journal is published on behalf of ChemPubSoc Europe, a group of 16 national chemical societies from within Europe, and supported by the Asian Chemical Editorial Societies. The ChemPubSoc Europe family comprises: Angewandte Chemie, Chemistry—A European Journal, European Journal of Organic Chemistry, European Journal of Inorganic Chemistry, ChemPhysChem, ChemBioChem, ChemMedChem, ChemCatChem, ChemSusChem, ChemPlusChem, ChemElectroChem, and ChemistryOpen.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信