Yiming Zou, Xuan Liu, Linzhi Du, Jiafan Yang, Zhishuang Liu, Zicheng Yuan, Lina Liu, Bicheng Yang, Zhe Shao, Igor A. Popov, Bin Hu
{"title":"使用直接取样和电离的微型质谱法现场分析复杂样品","authors":"Yiming Zou, Xuan Liu, Linzhi Du, Jiafan Yang, Zhishuang Liu, Zicheng Yuan, Lina Liu, Bicheng Yang, Zhe Shao, Igor A. Popov, Bin Hu","doi":"10.1002/rcm.10056","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Rationale</h3>\n \n <p>Miniature mass spectrometry (mini-MS) is a powerful method for onsite analysis of complex. The onsite sampling/ionization approach is critical in rapid screening of complex samples by mini-MS in field environments. Therefore, new development of direct ionization/sampling method coupled with mini-MS is needed for direct sample analysis.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A direct sampling/ionization kit using wooden tip or plant tissue was developed to couple with mini-MS for onsite analysis of complex samples. Targeted analytes were detected and identified by mini-MS/MS.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Various raw samples including powders, liquid, and viscous samples were directly sampled and ionized using wooden tip. Direct pesticide detection in juice was used to further evaluate the analytical performances of the newly developed wooden tip kit, obtaining excellent sensitivity, reproducibility, and quantitation capacity for direct sample analysis. Furthermore, direct tissue analysis was also successful demonstrated by direct ionization, showing a fast, simple, and efficient method for onsite analysis of biological tissue.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Overall, our data showed that this direct sampling/ionization method using wooden tip or plant tissue coupled with mini-MS approach is simple, fast, and sensitive method for onsite direct analysis of raw samples in field environments.</p>\n </section>\n </div>","PeriodicalId":225,"journal":{"name":"Rapid Communications in Mass Spectrometry","volume":"39 16","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Onsite Analysis of Complex Samples Using Miniature Mass Spectrometry With Direct Sampling and Ionization\",\"authors\":\"Yiming Zou, Xuan Liu, Linzhi Du, Jiafan Yang, Zhishuang Liu, Zicheng Yuan, Lina Liu, Bicheng Yang, Zhe Shao, Igor A. Popov, Bin Hu\",\"doi\":\"10.1002/rcm.10056\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Rationale</h3>\\n \\n <p>Miniature mass spectrometry (mini-MS) is a powerful method for onsite analysis of complex. The onsite sampling/ionization approach is critical in rapid screening of complex samples by mini-MS in field environments. Therefore, new development of direct ionization/sampling method coupled with mini-MS is needed for direct sample analysis.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A direct sampling/ionization kit using wooden tip or plant tissue was developed to couple with mini-MS for onsite analysis of complex samples. Targeted analytes were detected and identified by mini-MS/MS.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Various raw samples including powders, liquid, and viscous samples were directly sampled and ionized using wooden tip. Direct pesticide detection in juice was used to further evaluate the analytical performances of the newly developed wooden tip kit, obtaining excellent sensitivity, reproducibility, and quantitation capacity for direct sample analysis. Furthermore, direct tissue analysis was also successful demonstrated by direct ionization, showing a fast, simple, and efficient method for onsite analysis of biological tissue.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Overall, our data showed that this direct sampling/ionization method using wooden tip or plant tissue coupled with mini-MS approach is simple, fast, and sensitive method for onsite direct analysis of raw samples in field environments.</p>\\n </section>\\n </div>\",\"PeriodicalId\":225,\"journal\":{\"name\":\"Rapid Communications in Mass Spectrometry\",\"volume\":\"39 16\",\"pages\":\"\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-05-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rapid Communications in Mass Spectrometry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/rcm.10056\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rapid Communications in Mass Spectrometry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/rcm.10056","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Onsite Analysis of Complex Samples Using Miniature Mass Spectrometry With Direct Sampling and Ionization
Rationale
Miniature mass spectrometry (mini-MS) is a powerful method for onsite analysis of complex. The onsite sampling/ionization approach is critical in rapid screening of complex samples by mini-MS in field environments. Therefore, new development of direct ionization/sampling method coupled with mini-MS is needed for direct sample analysis.
Methods
A direct sampling/ionization kit using wooden tip or plant tissue was developed to couple with mini-MS for onsite analysis of complex samples. Targeted analytes were detected and identified by mini-MS/MS.
Results
Various raw samples including powders, liquid, and viscous samples were directly sampled and ionized using wooden tip. Direct pesticide detection in juice was used to further evaluate the analytical performances of the newly developed wooden tip kit, obtaining excellent sensitivity, reproducibility, and quantitation capacity for direct sample analysis. Furthermore, direct tissue analysis was also successful demonstrated by direct ionization, showing a fast, simple, and efficient method for onsite analysis of biological tissue.
Conclusions
Overall, our data showed that this direct sampling/ionization method using wooden tip or plant tissue coupled with mini-MS approach is simple, fast, and sensitive method for onsite direct analysis of raw samples in field environments.
期刊介绍：
Rapid Communications in Mass Spectrometry is a journal whose aim is the rapid publication of original research results and ideas on all aspects of the science of gas-phase ions; it covers all the associated scientific disciplines. There is no formal limit on paper length ("rapid" is not synonymous with "brief"), but papers should be of a length that is commensurate with the importance and complexity of the results being reported. Contributions may be theoretical or practical in nature; they may deal with methods, techniques and applications, or with the interpretation of results; they may cover any area in science that depends directly on measurements made upon gaseous ions or that is associated with such measurements.
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