kineins -5马达促进微管聚合的建模研究

Ping Xie
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引用次数: 0

摘要

Kinesin-5 Eg5电机具有促进微管聚合的能力。然而,Eg5马达如何促进微管聚合尚不清楚。本文建立了一个模型,在此基础上对Eg5马达促进微管聚合的动力学进行了分析研究。为了比较,我们还分析了微管聚合在有马达马达和没有马达马达的情况下的动力学。分析结果定量地解释了现有的实验数据。并给出了预测结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Modeling Studies of Microtubule Polymerization Promoted by Kinesin-5 Motors

Modeling Studies of Microtubule Polymerization Promoted by Kinesin-5 Motors

Kinesin-5 Eg5 motors have the ability to promote microtubule polymerization. However, how the Eg5 motors can promote the microtubule polymerization is unclear. Here, a model is presented, based on which the dynamics of the microtubule polymerization promoted by the Eg5 motors is studied analytically. For comparison, the dynamics of the microtubule polymerization in the presence of kinesin-1 motors and in the absence of the kinesin motor is also studied analytically. The analytical results explain quantitatively the available experimental data. The predicted results are also provided.

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