直肠神经鞘瘤样/Verocay体突出型良性平滑肌瘤1例报告

Alan King Lun Liu, Joanne Chapman
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引用次数: 0

摘要

Verocay小体通常在神经鞘瘤中发现,通常被认为是病变的典型特征,但它们不是典型的,偶尔可以在其他肿瘤中发现,包括胃肠道内的平滑肌瘤和胃肠道间质瘤(GIST)。因此,重要的是要记住这种鉴别诊断,并利用免疫组织化学小组来帮助诊断。我们在此报告一个罕见的62岁男性病例,在直肠指检中发现偶然的直肠肿块,并出现下尿路症状增加。直肠肿块的组织学显示梭形细胞增生,在整个标本中可见明显的Verocay小体。免疫组化示肌动蛋白和desmin阳性,S100、DOG1、CD34和CD117 (c-KIT)阴性,证实为Verocay体突出型平滑肌瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A case report on a schwannoma-like/Verocay body-prominent benign leiomyoma in the rectum
Verocay bodies are typically found in schwannoma and are often heralded as classical features of the lesion but they are not pathognomonic and can occasionally be found in other neoplasms, including leiomyomas and gastrointestinal stromal tumours (GIST) within the gastrointestinal (GI) tract. Hence, it is important to bear this differential diagnosis in mind and utilize an immunohistochemical panel to aid with the diagnosis. Here we present an unusual case of a 62-year-old male with an incidental rectal mass found on digital rectal examination upon presenting to urology with increased lower urinary tract symptoms. Histology of the rectal mass showed a spindle cell proliferation with prominent Verocay bodies seen throughout the specimen. Immunohistochemistry demonstrated that the tumour was positive for actin and desmin, negative for S100, DOG1, CD34 and CD117 (c-KIT), confirming it to being a Verocay body-prominent leiomyoma.
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来源期刊
Diagnostic Histopathology
Diagnostic Histopathology Medicine-Pathology and Forensic Medicine
CiteScore
1.30
自引率
0.00%
发文量
64
期刊介绍: This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.
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