水飞蓟素/水飞蓟宾素对电离辐射的辐射防护和辐射敏化特性

IF 2.9 4区医学 Q2 PATHOLOGY

Pathology, research and practice Pub Date : 2025-05-07 DOI:10.1016/j.prp.2025.156002

Faezeh Arghidash , Fatemeh Gheybi , Hamid Gholamhosseinian , Prashant Kesharwani , Amirhossein Sahebkar

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引用次数: 0

摘要

癌症是世界面临的一项健康和治疗挑战，正在作出许多努力，为所有形式的癌症制定治疗方案。放射治疗（RT）是一种癌症治疗方法，尽管它对杀死癌细胞有积极的作用，但会对健康细胞产生毒性。癌细胞有可能对放射治疗产生抗药性。为了解决这些问题，联合治疗可能是有益的。将植物与常规癌症治疗相结合是一种可行的选择，它们的潜力可以在这一领域得到利用。水飞蓟素及其有效成分水飞蓟宾的治疗作用已在传统医学中被广泛应用。本文旨在探讨水飞蓟素/水飞蓟宾在癌症治疗中的放射防护和放射增敏特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Radioprotective and radiosensitizing properties of silymarin/silibinin in response to ionizing radiation

Cancer is a health and treatment challenge that the world is facing, and many efforts are being made to develop treatment solutions for all forms of cancer. Radiotherapy (RT), one of the cancer treatment methods, can cause toxicity in healthy cells, even though it has positive effects on killing cancer cells. It is possible for cancer cells to develop resistance to radiotherapy. To address these issues, it can be beneficial to combine treatments. Combining plants with conventional cancer treatment is a viable option, and their potential can be utilized in this area. The therapeutic properties of silymarin and its active ingredient silibinin have been used in traditional medicine for a long time. The purpose of this review is to investigate the radioprotective and radio-sensitizing properties of silymarin/silibinin in cancer treatment.

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来源期刊

Pathology, research and practice 医学-病理学

CiteScore

5.00

自引率

3.60%

发文量

405

审稿时长

24 days

期刊介绍： Pathology, Research and Practice provides accessible coverage of the most recent developments across the entire field of pathology: Reviews focus on recent progress in pathology, while Comments look at interesting current problems and at hypotheses for future developments in pathology. Original Papers present novel findings on all aspects of general, anatomic and molecular pathology. Rapid Communications inform readers on preliminary findings that may be relevant for further studies and need to be communicated quickly. Teaching Cases look at new aspects or special diagnostic problems of diseases and at case reports relevant for the pathologist''s practice.