快速溶解的纳米纤维面膜,用于输送护肤成分

IF 5.4 2区 医学 Q1 BIOPHYSICS
Gengxin Liu , Juan Li , Lu Wang , Ling Zhang , Tingting Yang , Yingfan Guo , Guorui Zhang , Siyu Ni , Lu Qiao , Huali Nie
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引用次数: 0

摘要

面膜被广泛用于护肤,但传统的湿式面膜通常需要防腐剂来防止微生物的生长,这可能会导致皮肤刺激和环境问题,因为过度包装造成的塑料废物。为了解决这些问题,我们开发了一种创新的,快速溶解的纳米纤维面膜,它提供姜黄素(Cur),一种有效的抗氧化剂,不需要防腐剂或添加剂。利用静电纺丝技术,聚乙烯吡咯烷酮纳米纤维面膜不仅可以作为一个储层,提高Cur的稳定性和溶解度,而且在接触极少量水分时迅速溶解,有效地将活性化合物释放到皮肤上。该膜具有很强的抗氧化性能,对DPPH自由基的清除率约为90% %,并且具有良好的生物相容性,如其温和的pH值,在成纤维细胞培养中具有较高的细胞活力,并且在HET-CAM检测中无刺激性。这种新颖的设计解决了面膜行业面临的主要挑战,例如对防腐剂、塑料废物的依赖以及活性成分的不稳定性,同时通过有针对性的输送Cur,提供了增强的护肤效果。我们的方法提供了一种安全、环保、有效的抗衰老和保护性护肤替代方案,与传统湿式面膜相比具有显著优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fast-dissolving nanofibrous facial masks for delivering skincare ingredients
Facial masks are widely used in skincare, but traditional wet masks often require preservatives to prevent microbial growth, which can cause skin irritation and environmental issues due to plastic waste from excessive packaging. To address these issues, we have developed an innovative, fast-dissolving nanofibrous facial mask that delivers curcumin (Cur), a potent antioxidant, without the need for preservatives or additives. Utilizing electrospinning technology, the polyvinylpyrrolidone nanofibrous mask not only serves as a reservoir that enhances the stability and solubility of Cur but also dissolves rapidly upon contact with minimal moisture, efficiently releasing the active compound onto the skin. The mask demonstrates strong antioxidant properties, with a DPPH radical scavenging rate of approximately 90 %, and excellent biocompatibility, as shown by its mild pH, high cell viability in fibroblast cultures, and non-irritating nature in HET-CAM assays. This novel design addresses key challenges in the facial mask industry, such as the reliance on preservatives, plastic waste, and the instability of active ingredients, while providing enhanced skincare benefits through the targeted delivery of Cur. Our approach offers a safe, eco-friendly, and effective alternative for anti-aging and protective skincare, with significant advantages over conventional wet masks.
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来源期刊
Colloids and Surfaces B: Biointerfaces
Colloids and Surfaces B: Biointerfaces 生物-材料科学:生物材料
CiteScore
11.10
自引率
3.40%
发文量
730
审稿时长
42 days
期刊介绍: Colloids and Surfaces B: Biointerfaces is an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin, having particular relevance to the medical, pharmaceutical, biotechnological, food and cosmetic fields. Submissions that: (1) deal solely with biological phenomena and do not describe the physico-chemical or colloid-chemical background and/or mechanism of the phenomena, and (2) deal solely with colloid/interfacial phenomena and do not have appropriate biological content or relevance, are outside the scope of the journal and will not be considered for publication. The journal publishes regular research papers, reviews, short communications and invited perspective articles, called BioInterface Perspectives. The BioInterface Perspective provide researchers the opportunity to review their own work, as well as provide insight into the work of others that inspired and influenced the author. Regular articles should have a maximum total length of 6,000 words. In addition, a (combined) maximum of 8 normal-sized figures and/or tables is allowed (so for instance 3 tables and 5 figures). For multiple-panel figures each set of two panels equates to one figure. Short communications should not exceed half of the above. It is required to give on the article cover page a short statistical summary of the article listing the total number of words and tables/figures.
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