轻度认知障碍老年人的最小脚趾清除率变异性：与健康对照的差异和舞蹈干预的效果

IF 2.2 3区医学 Q3 NEUROSCIENCES

Gait & posture Pub Date : 2025-05-01 DOI:10.1016/j.gaitpost.2025.04.033

Berit K. Labott , Fabian Herold , Corinna Langhans , Nicole Halfpaap , Bernhard Grässler , Anita Hökelmann , Notger G. Müller , Daniel Hamacher

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引用次数: 0

摘要

患有轻度认知障碍（MCI）的老年人跌倒是一个主要的健康问题。对于健康个体，步态中最小脚趾间隙（MTC）的较高变异性与绊倒相关跌倒的风险相关，舞蹈干预可降低MTC变异性。对于轻度认知障碍患者来说，缺乏这样的经验证据。研究问题：我们旨在评估健康老年人和轻度认知损伤老年人之间MTC变异性的差异。此外，我们分析了六个月舞蹈干预对老年轻度认知损伤患者MTC变异性的影响。方法招募社区认知健康对照（n=34）和MCI患者（n=55）。所有参与者都使用惯性传感器进行步态评估。在一项队列研究中，使用Welch t检验比较健康和轻度认知障碍参与者的MTC变异性。除了认知表现外，参与者的特征没有显著差异。在一项随机对照试验中，MCI患者被随机分配到干预组（IG, n=27）或被动对照组（CG, n=28）。IG被要求参加为期六个月的每周两次90分钟的舞蹈课程。六个月后，在两组MCI参与者中重复步态评估，并使用2水平随机截距模型评估舞蹈干预对MTC变异性的影响。此外，在二次分析中分析了平均MTC。结果与健康成人相比，MCI患者的MTC变异性明显更高(p=。016, d=0.53)，但平均MTC无差异（p= 0.53）。980年,d< 0.01)。舞蹈干预没有改善MTC变异性（p=.182）或平均MTC （p=.742）。意义：与健康对照相比，老年轻度认知损伤患者的MTC变异性较高，可能导致其跌倒风险较高。未来的研究应该调查个性化舞蹈干预和其他干预方法对MTC变异性和跌倒风险的影响。

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Minimum Toe Clearance Variability in Older Adults with Mild Cognitive Impairment: Differences to Healthy Controls and Effects of a Dance Intervention

Background

Falls in older adults with mild cognitive impairment (MCI) are a major health issue. For healthy individuals, higher variability in minimum toe clearance (MTC) during gait is associated with the risk of tripping-related falls and dance intervention reduces MTC variability. Such empirical evidence is lacking for individuals with MCI.

Research Question

We aimed to assess differences in MTC variability between healthy older adults and older adults with MCI. Furthermore, we analysed the effects of a six-month dance intervention on MTC variability in older adults with MCI.

Methods

We recruited community-dwelling cognitively healthy control participants (n=34) and participants with MCI (n=55). All participants underwent gait assessment using inertial sensors. In a cohort study, MTC variability of healthy vs. MCI participants was compared using Welch’s t-test. There were no significant differences in the participant’s characteristics except for cognitive performance. In a randomised controlled trial, participants with MCI were randomly allocated to either an intervention (IG, n=27) or a passive control group (CG, n=28). IG was required to attend a twice-weekly 90-minute dance program for six months. After six months, the gait assessment was repeated in both groups of MCI participants, and the effect of the dance intervention on MTC variability was assessed using 2-level random intercept models. Additionally, the mean MTC was analysed in a secondary analysis.

Results

Adults with MCI exhibited a significantly higher MTC variability compared to healthy adults (p=.016, d=0.53), but no difference was found in the mean MTC (p=.980, d<0.01). The dance intervention did not improve either MTC variability (p=.182) or mean MTC (p=.742).

Significance

The higher MTC variability in older adults with MCI compared to healthy controls may contribute to their higher fall risk. Future studies should investigate the effects of an individually tailored dance intervention, and other intervention approaches on MTC variability and fall risk.

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来源期刊

Gait & posture 医学-神经科学

CiteScore

4.70

自引率

12.50%

发文量

616

审稿时长

6 months

期刊介绍： Gait & Posture is a vehicle for the publication of up-to-date basic and clinical research on all aspects of locomotion and balance. The topics covered include: Techniques for the measurement of gait and posture, and the standardization of results presentation; Studies of normal and pathological gait; Treatment of gait and postural abnormalities; Biomechanical and theoretical approaches to gait and posture; Mathematical models of joint and muscle mechanics; Neurological and musculoskeletal function in gait and posture; The evolution of upright posture and bipedal locomotion; Adaptations of carrying loads, walking on uneven surfaces, climbing stairs etc; spinal biomechanics only if they are directly related to gait and/or posture and are of general interest to our readers; The effect of aging and development on gait and posture; Psychological and cultural aspects of gait; Patient education.