{"title":"1例2型自身免疫性胰腺炎提示两种潜在的疾病活动标志物","authors":"Kazuki Natsui , Seiichi Yoshikawa , Ayano Kagata , Yusuke Horibata , Hiroyuki Usuda , Manabu Takeuchi , Shuji Terai","doi":"10.1016/j.gastha.2025.100635","DOIUrl":null,"url":null,"abstract":"<div><div>Autoimmune pancreatitis (AIP) is divided into 2 main subtypes: type 1 AIP (AIP-1) and type 2 AIP (AIP-2). This report describes a young woman diagnosed with AIP-2 using endoscopic ultrasound–guided tissue acquisition. AIP-2 has been reported less frequently than AIP-1 as serologic abnormalities and other organ involvement except for inflammatory bowel disease are absent. Additional laboratory analyses suggest that serum interleukin-8 and leucine-rich alpha-2 glycoprotein are more efficient disease activity biomarkers than conventional C-reactive proteins. We hope that this case report will contribute to the discovery of diagnostic biomarkers for AIP-2.</div></div>","PeriodicalId":73130,"journal":{"name":"Gastro hep advances","volume":"4 6","pages":"Article 100635"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Case of Type 2 Autoimmune Pancreatitis Suggesting Two Potential Disease Activity Markers\",\"authors\":\"Kazuki Natsui , Seiichi Yoshikawa , Ayano Kagata , Yusuke Horibata , Hiroyuki Usuda , Manabu Takeuchi , Shuji Terai\",\"doi\":\"10.1016/j.gastha.2025.100635\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Autoimmune pancreatitis (AIP) is divided into 2 main subtypes: type 1 AIP (AIP-1) and type 2 AIP (AIP-2). This report describes a young woman diagnosed with AIP-2 using endoscopic ultrasound–guided tissue acquisition. AIP-2 has been reported less frequently than AIP-1 as serologic abnormalities and other organ involvement except for inflammatory bowel disease are absent. Additional laboratory analyses suggest that serum interleukin-8 and leucine-rich alpha-2 glycoprotein are more efficient disease activity biomarkers than conventional C-reactive proteins. We hope that this case report will contribute to the discovery of diagnostic biomarkers for AIP-2.</div></div>\",\"PeriodicalId\":73130,\"journal\":{\"name\":\"Gastro hep advances\",\"volume\":\"4 6\",\"pages\":\"Article 100635\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gastro hep advances\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772572325000226\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gastro hep advances","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772572325000226","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Case of Type 2 Autoimmune Pancreatitis Suggesting Two Potential Disease Activity Markers
Autoimmune pancreatitis (AIP) is divided into 2 main subtypes: type 1 AIP (AIP-1) and type 2 AIP (AIP-2). This report describes a young woman diagnosed with AIP-2 using endoscopic ultrasound–guided tissue acquisition. AIP-2 has been reported less frequently than AIP-1 as serologic abnormalities and other organ involvement except for inflammatory bowel disease are absent. Additional laboratory analyses suggest that serum interleukin-8 and leucine-rich alpha-2 glycoprotein are more efficient disease activity biomarkers than conventional C-reactive proteins. We hope that this case report will contribute to the discovery of diagnostic biomarkers for AIP-2.
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