Jaime Alberto Coral Enríquez , Victoria Eugenia Cajas Bravo
{"title":"与系统性红斑狼疮相关的冷凝集素引起的自身免疫性溶血性贫血个案报告及文献回顾","authors":"Jaime Alberto Coral Enríquez , Victoria Eugenia Cajas Bravo","doi":"10.1016/j.rcreue.2024.12.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Cold agglutinin autoimmune haemolytic anaemia (AIHA) secondary to systemic lupus erythematosus (SLE) is a rare manifestation. There are no cohorts or case series that allow us to evaluate the characteristics of this group of patients.</div></div><div><h3>Objective</h3><div>To describe the clinical and serological characteristics of patients with systemic lupus erythematosus (SLE) and cold agglutinin hemolytic anemia.</div></div><div><h3>Materials and methods</h3><div>We present two cases with SLE that debuted with cold agglutinin AHAI, their clinical and immunological profile and response to immunosuppressive treatment.</div></div><div><h3>Results</h3><div>Eleven cases reported in the literature from 1950 to 2023 are described.</div></div><div><h3>Conclusion</h3><div>Cold agglutinin AIHA secondary to SLE is rare, with unclear clinical features compared to idiopathic forms and usually not associated with manifestations or serious organic involvement.</div></div>","PeriodicalId":101099,"journal":{"name":"Revista Colombiana de Reumatología (English Edition)","volume":"32 2","pages":"Pages 173-179"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Autoimmune haemolytic anaemia due to cold agglutinins associated with systemic lupus erythematosus. Case presentation and literature review\",\"authors\":\"Jaime Alberto Coral Enríquez , Victoria Eugenia Cajas Bravo\",\"doi\":\"10.1016/j.rcreue.2024.12.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Cold agglutinin autoimmune haemolytic anaemia (AIHA) secondary to systemic lupus erythematosus (SLE) is a rare manifestation. There are no cohorts or case series that allow us to evaluate the characteristics of this group of patients.</div></div><div><h3>Objective</h3><div>To describe the clinical and serological characteristics of patients with systemic lupus erythematosus (SLE) and cold agglutinin hemolytic anemia.</div></div><div><h3>Materials and methods</h3><div>We present two cases with SLE that debuted with cold agglutinin AHAI, their clinical and immunological profile and response to immunosuppressive treatment.</div></div><div><h3>Results</h3><div>Eleven cases reported in the literature from 1950 to 2023 are described.</div></div><div><h3>Conclusion</h3><div>Cold agglutinin AIHA secondary to SLE is rare, with unclear clinical features compared to idiopathic forms and usually not associated with manifestations or serious organic involvement.</div></div>\",\"PeriodicalId\":101099,\"journal\":{\"name\":\"Revista Colombiana de Reumatología (English Edition)\",\"volume\":\"32 2\",\"pages\":\"Pages 173-179\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Colombiana de Reumatología (English Edition)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2444440524001596\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Colombiana de Reumatología (English Edition)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2444440524001596","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Autoimmune haemolytic anaemia due to cold agglutinins associated with systemic lupus erythematosus. Case presentation and literature review
Introduction
Cold agglutinin autoimmune haemolytic anaemia (AIHA) secondary to systemic lupus erythematosus (SLE) is a rare manifestation. There are no cohorts or case series that allow us to evaluate the characteristics of this group of patients.
Objective
To describe the clinical and serological characteristics of patients with systemic lupus erythematosus (SLE) and cold agglutinin hemolytic anemia.
Materials and methods
We present two cases with SLE that debuted with cold agglutinin AHAI, their clinical and immunological profile and response to immunosuppressive treatment.
Results
Eleven cases reported in the literature from 1950 to 2023 are described.
Conclusion
Cold agglutinin AIHA secondary to SLE is rare, with unclear clinical features compared to idiopathic forms and usually not associated with manifestations or serious organic involvement.
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