非结核性分枝杆菌淋巴结炎的婴儿与高IgM综合征：一个罕见的病例报告

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2025-04-28 DOI:10.1016/j.diagmicrobio.2025.116871

Chunyan Zhao , Chang Song , Xianzhen Huang , Xiayan Meng , Aichun Huang , Chaoyan Xu , Lili Luo , Shaoyong Xi , Yanqun Lan , Weiwen Li , Qingdong Zhu

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引用次数: 0

摘要

高免疫球蛋白M综合征是罕见的。我们报告一个7个月大的婴儿谁患有高免疫球蛋白M综合征和发展非结核分枝杆菌（NTM）淋巴结炎。前者被下一代测序证实为x连锁隐性，而最初的免疫球蛋白测试显示高IgM水平。后者通过淋巴结脓液抗酸染色涂片、培养和PCR诊断。这个孩子接受了治疗。同时，他接受了免疫支持治疗。患儿随访11个月，病情进展良好。

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Non-tuberculous mycobacterial lymphadenitis in an infant with Hyper IgM Syndrome: A rare case report

Hyper Immunoglobulin M syndrome is rare. We report a 7-month-old infant who suffered Hyper Immunoglobulin M syndrome and developed non-tuberculous mycobacterial (NTM) lymphadenitis. The former was confirmed by next-generation sequencing revealed X-linked recessive, whilst initial immunoglobulin testing displayed high IgM levels. The latter was diagnosed by lymph node pus acid-fast staining smear, culture and PCR. The child received therapy. Meanwhile, he was treated with immune supporting. The child was followed up for 11 months, and he progressed well.

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.