纯苯活化使非活化芳烃选择性脱芳(氘)氢二氟烷基化成为可能

IF 9.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Xu Jiang, Jie-Chen Guo, Ming-Yang Wang, Hao-Song Wang, Chu-Qiao Li & Wei LiZhejiang University, Department of Chemistry, Hangzhou 310058
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引用次数: 0

摘要

CCS化学,领先于印刷。二氟烷基官能团在药物发现中的普遍存在刺激了二氟烷基化反应的巨大进步。然而,芳烃的脱芳氢二氟烷基化仍然是一个未解决的问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exclusive Benzene Activation Enables Selective Dearomative (Deutero)Hydrodifluoroalkylation of Nonactivated Arenes
CCS Chemistry, Ahead of Print.
The prevalence of difluoroalkyl functionalities in drug discovery has stimulated tremendous advances in difluoroalkylation reactions. However, the dearomative hydrodifluoroalkylation of arenes remains an unsolved task due to the severe challenges in ...
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来源期刊
CCS Chemistry
CCS Chemistry Chemistry-General Chemistry
CiteScore
13.60
自引率
13.40%
发文量
475
审稿时长
10 weeks
期刊介绍: CCS Chemistry, the flagship publication of the Chinese Chemical Society, stands as a leading international chemistry journal based in China. With a commitment to global outreach in both contributions and readership, the journal operates on a fully Open Access model, eliminating subscription fees for contributing authors. Issued monthly, all articles are published online promptly upon reaching final publishable form. Additionally, authors have the option to expedite the posting process through Immediate Online Accepted Article posting, making a PDF of their accepted article available online upon journal acceptance.
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