胰腺癌的神经交叉：伤害感受器如何驱动肿瘤进展和免疫逃避

IF 28.1 1区生物学 Q1 CELL BIOLOGY

Cell Research Pub Date : 2025-05-07 DOI:10.1038/s41422-025-01124-5

Carmen Mota Reyes, Helmut Friess, Ihsan Ekin Demir

引用次数: 0

摘要

痛觉感受器神经元通过与癌症相关成纤维细胞相互作用抑制免疫反应，积极促进胰腺导管腺癌的进展。靶向它们的信号通路为增强抗肿瘤免疫和治疗癌症疼痛提供了一种新的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Research 生物-细胞生物学

CiteScore

53.90

自引率

0.70%

发文量

2420

审稿时长

2.3 months

期刊介绍： Cell Research (CR) is an international journal published by Springer Nature in partnership with the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS). It focuses on publishing original research articles and reviews in various areas of life sciences, particularly those related to molecular and cell biology. The journal covers a broad range of topics including cell growth, differentiation, and apoptosis; signal transduction; stem cell biology and development; chromatin, epigenetics, and transcription; RNA biology; structural and molecular biology; cancer biology and metabolism; immunity and molecular pathogenesis; molecular and cellular neuroscience; plant molecular and cell biology; and omics, system biology, and synthetic biology. CR is recognized as China's best international journal in life sciences and is part of Springer Nature's prestigious family of Molecular Cell Biology journals.