蛋白质杀手药物如何战胜一些最严重的癌症

IF 50.5 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Nature Pub Date : 2025-05-07 DOI:10.1038/d41586-025-01350-2

Ken Garber

引用次数: 0

摘要

PROTAC疗法的发展势头正在增强，这种疗法可以消除致病蛋白质，包括那些导致难以治疗的儿童癌症的蛋白质。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

How protein-slayer drugs could beat some of the cruellest cancers

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How protein-slayer drugs could beat some of the cruellest cancers

Momentum is building for PROTAC treatments that eliminate disease-causing proteins, including those responsible for difficult-to-treat childhood cancers. Momentum is building for PROTAC treatments that eliminate disease-causing proteins, including those responsible for difficult-to-treat childhood cancers.

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来源期刊

Nature 综合性期刊-综合性期刊

CiteScore

90.00

自引率

1.20%

发文量

3652

审稿时长

3 months

期刊介绍： Nature is a prestigious international journal that publishes peer-reviewed research in various scientific and technological fields. The selection of articles is based on criteria such as originality, importance, interdisciplinary relevance, timeliness, accessibility, elegance, and surprising conclusions. In addition to showcasing significant scientific advances, Nature delivers rapid, authoritative, insightful news, and interpretation of current and upcoming trends impacting science, scientists, and the broader public. The journal serves a dual purpose: firstly, to promptly share noteworthy scientific advances and foster discussions among scientists, and secondly, to ensure the swift dissemination of scientific results globally, emphasizing their significance for knowledge, culture, and daily life.