Wenlong Hou , Wenwen Liu , Mengtian Tan , Jiaxu Fang , Keye Cao , Xincheng Du , Haijun Zhang
{"title":"肌腱组织工程的历史演变、热点和趋势:文献计量学分析","authors":"Wenlong Hou , Wenwen Liu , Mengtian Tan , Jiaxu Fang , Keye Cao , Xincheng Du , Haijun Zhang","doi":"10.1016/j.reth.2025.04.009","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>As a significant branch of tissue engineering, tendon tissue engineering has developed rapidly, driven by advancements in new technologies and the refinement of medical theories. This study summarizes its development by analyzing historical evolution, research hotspots, and future trends to reveal core research directions and potential pathways.</div></div><div><h3>Methods</h3><div>Based on literature from WoS CC (1991–2024) and analyzed using VOSviewer, CiteSpace, and Bibliometrix, the study evaluates publication trends and research patterns.</div></div><div><h3>Results</h3><div>Findings show continuous growth in annual publications. The United States and China are key contributors with close collaboration. Chang James is the most prolific author, and stable research teams have emerged, though inter-team cooperation remains limited. Acta Biomaterialia publishes the most papers in this field, characterized by interdisciplinary integration. Key research focuses include scaffolds, seed cells, and rotator cuff injuries. Frontiers involve ideal scaffold construction, tendon adhesion prevention, and regeneration strategies. Future directions emphasize novel biomaterials, tendon-bone interface healing, innovative seed cell cultivation, tendon growth microenvironment construction, and clinical translation of research outcomes.</div></div><div><h3>Conclusion</h3><div>This bibliometric analysis reveals the core research directions and potential pathways in tendon tissue engineering, providing a reference for future studies.</div></div>","PeriodicalId":20895,"journal":{"name":"Regenerative Therapy","volume":"29 ","pages":"Pages 600-612"},"PeriodicalIF":3.5000,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Historical evolution, hotspots, and trends in tendon tissue engineering: A bibliometric analysis\",\"authors\":\"Wenlong Hou , Wenwen Liu , Mengtian Tan , Jiaxu Fang , Keye Cao , Xincheng Du , Haijun Zhang\",\"doi\":\"10.1016/j.reth.2025.04.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>As a significant branch of tissue engineering, tendon tissue engineering has developed rapidly, driven by advancements in new technologies and the refinement of medical theories. This study summarizes its development by analyzing historical evolution, research hotspots, and future trends to reveal core research directions and potential pathways.</div></div><div><h3>Methods</h3><div>Based on literature from WoS CC (1991–2024) and analyzed using VOSviewer, CiteSpace, and Bibliometrix, the study evaluates publication trends and research patterns.</div></div><div><h3>Results</h3><div>Findings show continuous growth in annual publications. The United States and China are key contributors with close collaboration. Chang James is the most prolific author, and stable research teams have emerged, though inter-team cooperation remains limited. Acta Biomaterialia publishes the most papers in this field, characterized by interdisciplinary integration. Key research focuses include scaffolds, seed cells, and rotator cuff injuries. Frontiers involve ideal scaffold construction, tendon adhesion prevention, and regeneration strategies. Future directions emphasize novel biomaterials, tendon-bone interface healing, innovative seed cell cultivation, tendon growth microenvironment construction, and clinical translation of research outcomes.</div></div><div><h3>Conclusion</h3><div>This bibliometric analysis reveals the core research directions and potential pathways in tendon tissue engineering, providing a reference for future studies.</div></div>\",\"PeriodicalId\":20895,\"journal\":{\"name\":\"Regenerative Therapy\",\"volume\":\"29 \",\"pages\":\"Pages 600-612\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-05-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Regenerative Therapy\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352320425000859\",\"RegionNum\":3,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CELL & TISSUE ENGINEERING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Regenerative Therapy","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352320425000859","RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
Historical evolution, hotspots, and trends in tendon tissue engineering: A bibliometric analysis
Introduction
As a significant branch of tissue engineering, tendon tissue engineering has developed rapidly, driven by advancements in new technologies and the refinement of medical theories. This study summarizes its development by analyzing historical evolution, research hotspots, and future trends to reveal core research directions and potential pathways.
Methods
Based on literature from WoS CC (1991–2024) and analyzed using VOSviewer, CiteSpace, and Bibliometrix, the study evaluates publication trends and research patterns.
Results
Findings show continuous growth in annual publications. The United States and China are key contributors with close collaboration. Chang James is the most prolific author, and stable research teams have emerged, though inter-team cooperation remains limited. Acta Biomaterialia publishes the most papers in this field, characterized by interdisciplinary integration. Key research focuses include scaffolds, seed cells, and rotator cuff injuries. Frontiers involve ideal scaffold construction, tendon adhesion prevention, and regeneration strategies. Future directions emphasize novel biomaterials, tendon-bone interface healing, innovative seed cell cultivation, tendon growth microenvironment construction, and clinical translation of research outcomes.
Conclusion
This bibliometric analysis reveals the core research directions and potential pathways in tendon tissue engineering, providing a reference for future studies.
期刊介绍:
Regenerative Therapy is the official peer-reviewed online journal of the Japanese Society for Regenerative Medicine.
Regenerative Therapy is a multidisciplinary journal that publishes original articles and reviews of basic research, clinical translation, industrial development, and regulatory issues focusing on stem cell biology, tissue engineering, and regenerative medicine.