激光表面纹理增强种植体生物相容性和骨整合:对其表面特性影响的重要回顾

IF 1.4 3区 医学 Q4 ENGINEERING, BIOMEDICAL
Sertan Ozan , Şefika Kasman , I. Can Uçar , Cuie Wen
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引用次数: 0

摘要

植入物的生物相容性是植入手术成功的一个重要因素,骨整合对于需要将周围骨组织直接粘附到植入物表面的骨整合植入物(如无骨水泥全髋关节假体)至关重要。骨整合受到几个因素的影响,包括表面特征(如微地形、表面化学、润湿性和粗糙度),它们共同影响种植体的稳定性,这是骨整合的关键因素。这些因素直接受到表面处理方法的影响,而表面处理方法在骨整合中起着至关重要的作用。激光表面变形是近年来发展起来的一种有效的表面处理技术。激光表面纹理通过热效应改变植入物的表面,包括微地形、化学成分、粗糙度和润湿性的变化。这些表面特征的改变提高了种植体的使用寿命和性能。激光表面纹理可用于制造具有改善成骨细胞粘附性和活性的种植体表面,同时增加抗菌能力。综述了激光表面纹理加工的研究进展,分析了激光表面纹理加工对表面性能和生物性能的影响。它评估了过去的研究和实验结果,激光表面变形在发展种植技术以改善临床结果方面的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Laser surface texturing for enhanced implant biocompatibility and osseointegration: A critical review of its effects on surface properties

Laser surface texturing for enhanced implant biocompatibility and osseointegration: A critical review of its effects on surface properties
An implant's biocompatibility is an important factor in the success of the implantation procedure, along with osseointegration, which is crucial for osseointegrated implants (e.g. cementless total hip prosthesis) that require direct adherence of surrounding bone tissue to the implant surface. Osseointegration is affected by several factors, including surface features (e.g. micro-topography, surface chemistry, wettability, and roughness) which collectively influence implant stability, a key element of osseointegration. These factors are directly impacted by surface preparation methods, which play a critical role in enhancing osseointegration. Laser surface texturing is an effective surface-preparation technique that has become common in recent times. Laser surface texturing alters an implant's surface through thermal effects, including changes in micro-topography, chemical composition, roughness, and wettability. These changes in surface characteristics improve the lifetime and performance of the implant. Laser surface texturing can be used to manufacture implant surfaces with improved osteoblast adherence and activity while increasing antibacterial capacity. This paper reviews the process of laser surface texturing and analyzes its impacts on surface properties and biological performance. It appraises past studies and experimental findings on the potential of laser surface texturing in developing implant technology for improvement in clinical outcomes.
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来源期刊
Clinical Biomechanics
Clinical Biomechanics 医学-工程:生物医学
CiteScore
3.30
自引率
5.60%
发文量
189
审稿时长
12.3 weeks
期刊介绍: Clinical Biomechanics is an international multidisciplinary journal of biomechanics with a focus on medical and clinical applications of new knowledge in the field. The science of biomechanics helps explain the causes of cell, tissue, organ and body system disorders, and supports clinicians in the diagnosis, prognosis and evaluation of treatment methods and technologies. Clinical Biomechanics aims to strengthen the links between laboratory and clinic by publishing cutting-edge biomechanics research which helps to explain the causes of injury and disease, and which provides evidence contributing to improved clinical management. A rigorous peer review system is employed and every attempt is made to process and publish top-quality papers promptly. Clinical Biomechanics explores all facets of body system, organ, tissue and cell biomechanics, with an emphasis on medical and clinical applications of the basic science aspects. The role of basic science is therefore recognized in a medical or clinical context. The readership of the journal closely reflects its multi-disciplinary contents, being a balance of scientists, engineers and clinicians. The contents are in the form of research papers, brief reports, review papers and correspondence, whilst special interest issues and supplements are published from time to time. Disciplines covered include biomechanics and mechanobiology at all scales, bioengineering and use of tissue engineering and biomaterials for clinical applications, biophysics, as well as biomechanical aspects of medical robotics, ergonomics, physical and occupational therapeutics and rehabilitation.
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