双曲叠加二元相位调制构造的中高强度超分辨聚焦超声

IF 3.4 2区物理与天体物理 Q1 ACOUSTICS

Applied Acoustics Pub Date : 2025-05-06 DOI:10.1016/j.apacoust.2025.110778

Yujin Liu , Zhentian Liu , Wei Yue , Qinyi Wang , Gepu Guo , Yuzhi Li , Qingyu Ma

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引用次数: 0

摘要

超振荡现象是突破衍射极限所必需的，它通常用巨大的边带来换取超分辨率聚焦。在这项研究中，引入双曲叠加二元相位调制方法，在水中实现中高强度超分辨率聚焦超声，频率为~ MHz。利用总结出的系统传输函数，考虑半最大全宽和旁瓣峰比这两个相互依赖的参数，对双曲叠加二相透镜进行了设计和优化。进一步分析了激励频率对焦距和超分辨性能的影响，实现了FWHM为0.42 λ/NA、SLPR为44%、压力增益为17.8的焦斑，并在0.8-1.2 MHz范围内实现了30 ~ 70 mm的灵活可调焦距。超分辨率成像和粒子操作验证了该方法的灵活性和鲁棒性，为高精度超声诊断和治疗的新突破铺平了道路。

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Medium to high intensity super-resolution focused ultrasound constructed by hyperbolic-superimposed binary phase modulation

Super-oscillatory phenomenon, essential for breaking the diffraction limit, often trades huge side-bands for a super-resolution focus. In this study, the hyperbolic-superimposed binary phase modulation method is introduced to achieve medium to high intensity super-resolution focused ultrasound in water at ∼ MHz frequencies. Utilizing the summarized system transmission function, the hyperbolic-superimposed binary phase lens is designed and optimized by considering the mutually dependent parameters of the full width at half maximum (FWHM) and side lobe to peak ratio (SLPR). The influence of excitation frequency on focal length and super-resolution performance is further analyzed, achieving a focal spot with FWHM of 0.42 λ/NA, SLPR of 44 %, and pressure gain of 17.8, along with a flexibly adjustable focal length from 30 to 70 mm within 0.8–1.2 MHz. The flexibility and robustness of the proposed method are validated by the super-resolution imaging and the particle manipulation, paving the way for new breakthroughs in high-precision ultrasonic diagnosis and treatment.

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来源期刊

Applied Acoustics 物理-声学

CiteScore

7.40

自引率

11.80%

发文量

618

审稿时长

7.5 months

期刊介绍： Since its launch in 1968, Applied Acoustics has been publishing high quality research papers providing state-of-the-art coverage of research findings for engineers and scientists involved in applications of acoustics in the widest sense. Applied Acoustics looks not only at recent developments in the understanding of acoustics but also at ways of exploiting that understanding. The Journal aims to encourage the exchange of practical experience through publication and in so doing creates a fund of technological information that can be used for solving related problems. The presentation of information in graphical or tabular form is especially encouraged. If a report of a mathematical development is a necessary part of a paper it is important to ensure that it is there only as an integral part of a practical solution to a problem and is supported by data. Applied Acoustics encourages the exchange of practical experience in the following ways: • Complete Papers • Short Technical Notes • Review Articles; and thereby provides a wealth of technological information that can be used to solve related problems. Manuscripts that address all fields of applications of acoustics ranging from medicine and NDT to the environment and buildings are welcome.