吡咯偶氮修饰的共价有机框架作为结构响应质谱探针用于复杂样品中痕量有毒化学物质的高灵敏度和高通量筛选

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-04-11 DOI:10.1039/d5cc01108f

Li Huang , Qian Wang , Qiu-Rong He , Xiu Huang , Zun-Zhen Zhang

引用次数: 0

摘要

采用聚偶氮修饰的共价有机骨架（Py-Azo-COF）作为SALDI-TOF质谱分析的结构响应探针。由于其独特的结构，Py-Azo-COF探针具有高亲和力、高灵敏度（LOD: 2-200 fg mL−1）、重复性、耐盐性和低本底干扰，能够有效筛选复杂样品中的各种痕量有毒化学物质。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Py-Azo-decorated covalent organic frameworks as a structure-responsive mass spectrometry probe for high-sensitivity and high-throughput screening of trace toxic chemicals in complex samples†

A Py-azo-decorated covalent organic framework (Py-Azo-COF) was utilized as a structure-responsive probe for SALDI-TOF MS analysis. Benefiting from its unique structure, the Py-Azo-COF probe exhibited high affinity, sensitivity (LOD: 2–200 fg mL⁻¹), reproducibility, salt tolerance, and low background interference, enabling efficient screening of diverse trace toxic chemicals in complex samples.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.