J. Andrade-Restrepo , D. Rubio-Cruz , J.G. Maigual-Quintas , S.G. Sicard-Gómez , E.J. Cuello-Navarro , L.C. Álvarez-Larrota , R. García-Duperly , E.E. Londoño-Schimmer , A.M. Rey-Rubiano , B. Mendoza de Molano , R.P. López-Panqueva
{"title":"哥伦比亚波哥大一家高级专科中心的炎性肠病患者的肠外表现和其他相关疾病的患病率","authors":"J. Andrade-Restrepo , D. Rubio-Cruz , J.G. Maigual-Quintas , S.G. Sicard-Gómez , E.J. Cuello-Navarro , L.C. Álvarez-Larrota , R. García-Duperly , E.E. Londoño-Schimmer , A.M. Rey-Rubiano , B. Mendoza de Molano , R.P. López-Panqueva","doi":"10.1016/j.rgmxen.2024.07.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and aims</h3><div>The prevalence and incidence of inflammatory bowel disease (IBD) has increased significantly in Latin America. Extraintestinal manifestations (EIMs) have elevated morbidity and are poorly characterized in the region. Our aim was to describe the characteristics of EIMs in patients with IBD at the <em>Hospital Universitario Fundación Santa Fe de Bogotá</em>, utilizing the EIM classification proposed by the European Crohn’s and Colitis Organisation (ECCO).</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study was conducted based on an institutional database of patients with IBD and the EIM definition used by the ECCO. Prevalence and prevalence ratios (PRs) of the EIMs were calculated.</div></div><div><h3>Results</h3><div>The study included 168 patients, 66 of whom were diagnosed with Crohn’s disease (CD) and 102 with ulcerative colitis (UC). A total of 30.4% patients had at least one EIM, and the most frequent were oral ulcers (13.7%), arthritis (10.1%), and uveitis/episcleritis (6.5%). There was a greater prevalence of EIMs in CD (31.8% vs 29.40% in UC) and women (32.47% vs 28.57% in men). There was a significant PR between uveitis/episcleritis and arthritis, erythema nodosum and arthritis, and erythema nodosum and other eye diseases.</div></div><div><h3>Conclusions</h3><div>Our study shows a high prevalence of EIMs, surpassing that of previous Colombian studies, with a predominance of CD. Oral manifestations stand out as the most common. Prevalence studies on EIMs in Colombia are needed to establish multidisciplinary specialized centers, improving the quality of life of patients with IBD.</div></div>","PeriodicalId":74705,"journal":{"name":"Revista de gastroenterologia de Mexico (English)","volume":"90 1","pages":"Pages 44-53"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of extraintestinal manifestations and other associated conditions in a cohort of patients with inflammatory bowel disease at an advanced specialty center in Bogotá, Colombia\",\"authors\":\"J. Andrade-Restrepo , D. Rubio-Cruz , J.G. Maigual-Quintas , S.G. Sicard-Gómez , E.J. Cuello-Navarro , L.C. Álvarez-Larrota , R. García-Duperly , E.E. Londoño-Schimmer , A.M. Rey-Rubiano , B. Mendoza de Molano , R.P. López-Panqueva\",\"doi\":\"10.1016/j.rgmxen.2024.07.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction and aims</h3><div>The prevalence and incidence of inflammatory bowel disease (IBD) has increased significantly in Latin America. Extraintestinal manifestations (EIMs) have elevated morbidity and are poorly characterized in the region. Our aim was to describe the characteristics of EIMs in patients with IBD at the <em>Hospital Universitario Fundación Santa Fe de Bogotá</em>, utilizing the EIM classification proposed by the European Crohn’s and Colitis Organisation (ECCO).</div></div><div><h3>Materials and methods</h3><div>A cross-sectional study was conducted based on an institutional database of patients with IBD and the EIM definition used by the ECCO. Prevalence and prevalence ratios (PRs) of the EIMs were calculated.</div></div><div><h3>Results</h3><div>The study included 168 patients, 66 of whom were diagnosed with Crohn’s disease (CD) and 102 with ulcerative colitis (UC). A total of 30.4% patients had at least one EIM, and the most frequent were oral ulcers (13.7%), arthritis (10.1%), and uveitis/episcleritis (6.5%). There was a greater prevalence of EIMs in CD (31.8% vs 29.40% in UC) and women (32.47% vs 28.57% in men). There was a significant PR between uveitis/episcleritis and arthritis, erythema nodosum and arthritis, and erythema nodosum and other eye diseases.</div></div><div><h3>Conclusions</h3><div>Our study shows a high prevalence of EIMs, surpassing that of previous Colombian studies, with a predominance of CD. Oral manifestations stand out as the most common. Prevalence studies on EIMs in Colombia are needed to establish multidisciplinary specialized centers, improving the quality of life of patients with IBD.</div></div>\",\"PeriodicalId\":74705,\"journal\":{\"name\":\"Revista de gastroenterologia de Mexico (English)\",\"volume\":\"90 1\",\"pages\":\"Pages 44-53\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista de gastroenterologia de Mexico (English)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2255534X25000131\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de gastroenterologia de Mexico (English)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2255534X25000131","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
简介和目的炎症性肠病(IBD)的患病率和发病率在拉丁美洲显著增加。肠外表现(EIMs)在该地区发病率高,特征不明显。我们的目的是利用欧洲克罗恩病和结肠炎组织(ECCO)提出的EIM分类,描述Fundación圣菲波哥大医院IBD患者的EIM特征。材料和方法基于IBD患者的机构数据库和ECCO使用的EIM定义进行了一项横断面研究。计算EIMs的患病率和患病率比(pr)。结果本研究纳入168例患者,其中66例诊断为克罗恩病(CD), 102例诊断为溃疡性结肠炎(UC)。共有30.4%的患者至少有一种EIM,最常见的是口腔溃疡(13.7%)、关节炎(10.1%)和葡萄膜炎/外巩膜炎(6.5%)。EIMs在CD (31.8% vs . 29.40% UC)和女性(32.47% vs . 28.57%男性)中患病率更高。葡萄膜炎/眼膜炎与关节炎、结节性红斑与关节炎、结节性红斑与其他眼病之间的PR值显著。结论sour研究显示EIMs的患病率较高,超过了之前哥伦比亚的研究,以CD为主,口腔表现最为常见。哥伦比亚需要对EIMs的患病率进行研究,以建立多学科的专业中心,提高IBD患者的生活质量。
Prevalence of extraintestinal manifestations and other associated conditions in a cohort of patients with inflammatory bowel disease at an advanced specialty center in Bogotá, Colombia
Introduction and aims
The prevalence and incidence of inflammatory bowel disease (IBD) has increased significantly in Latin America. Extraintestinal manifestations (EIMs) have elevated morbidity and are poorly characterized in the region. Our aim was to describe the characteristics of EIMs in patients with IBD at the Hospital Universitario Fundación Santa Fe de Bogotá, utilizing the EIM classification proposed by the European Crohn’s and Colitis Organisation (ECCO).
Materials and methods
A cross-sectional study was conducted based on an institutional database of patients with IBD and the EIM definition used by the ECCO. Prevalence and prevalence ratios (PRs) of the EIMs were calculated.
Results
The study included 168 patients, 66 of whom were diagnosed with Crohn’s disease (CD) and 102 with ulcerative colitis (UC). A total of 30.4% patients had at least one EIM, and the most frequent were oral ulcers (13.7%), arthritis (10.1%), and uveitis/episcleritis (6.5%). There was a greater prevalence of EIMs in CD (31.8% vs 29.40% in UC) and women (32.47% vs 28.57% in men). There was a significant PR between uveitis/episcleritis and arthritis, erythema nodosum and arthritis, and erythema nodosum and other eye diseases.
Conclusions
Our study shows a high prevalence of EIMs, surpassing that of previous Colombian studies, with a predominance of CD. Oral manifestations stand out as the most common. Prevalence studies on EIMs in Colombia are needed to establish multidisciplinary specialized centers, improving the quality of life of patients with IBD.