Irin Kwananocha , Joëll Magré , Femke Verseijden , Amir S. Kamali , Saber Amin Yavari , Saskia G.M. Plomp , Ralph J.B. Sakkers , Marianna A. Tryfonidou , Harrie Weinans , Koen Willemsen , Bart C.H. van der Wal , Björn P. Meij
{"title":"使用现成的3d打印钛髋臼边缘扩展植入物治疗犬髋关节发育不良的初步研究","authors":"Irin Kwananocha , Joëll Magré , Femke Verseijden , Amir S. Kamali , Saber Amin Yavari , Saskia G.M. Plomp , Ralph J.B. Sakkers , Marianna A. Tryfonidou , Harrie Weinans , Koen Willemsen , Bart C.H. van der Wal , Björn P. Meij","doi":"10.1016/j.rvsc.2025.105668","DOIUrl":null,"url":null,"abstract":"<div><div>Hip dysplasia (HD) is one of the most prevalent orthopedic issues in dogs. Generic shelf implants are 3D-printed devices designed to address HD in dogs of varying sizes and hip laxity scores. This pilot study evaluated the feasibility and effectiveness of generic shelf implants in six dogs diagnosed with bilateral HD. Each dog underwent bilateral hip surgery in a single session followed by a 12-month monitoring period.</div><div>Post-operative CT scans revealed increased femoral head coverage in all 12 hips, resulting in reversed hip laxity. However, implants exhibited positional deviations from optimal congruency for 5.1 ± 1.7 mm. Mild to moderate osteoarthritis (OA) progression was observed during the lead times and post-operatively. Although force plate analysis showed no significant changes, functional outcomes improved, as demonstrated by reduced owner questionnaire scores at 12 months post-surgery. Post-operative internal rotation and abduction angles were reduced compared to pre-operative values, suggesting potential impingement due to implant positioning. Complications were observed in one dog (two hips). Another dog died nine months post-surgery due to unrelated causes. Post-mortem histology and micro-CT analysis of these hip joints revealed localized cartilage depletion around the implant's rim extension area. However, no lameness or hip discomfort was reported by the owner before the dog's death.</div><div>The generic shelf implant effectively enhances hip stability and alleviates pain-related behaviors by improving femoral head coverage. Suboptimal placement was associated with reduced range of motion and OA progression in this study. Refinements to the implant design and adjusting sizing protocols to better match acetabular morphology are necessary.</div></div>","PeriodicalId":21083,"journal":{"name":"Research in veterinary science","volume":"191 ","pages":"Article 105668"},"PeriodicalIF":2.2000,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pilot study on the use of an off-the-shelf 3D-printed titanium acetabular rim extension implant for treating canine hip dysplasia\",\"authors\":\"Irin Kwananocha , Joëll Magré , Femke Verseijden , Amir S. Kamali , Saber Amin Yavari , Saskia G.M. Plomp , Ralph J.B. Sakkers , Marianna A. Tryfonidou , Harrie Weinans , Koen Willemsen , Bart C.H. van der Wal , Björn P. Meij\",\"doi\":\"10.1016/j.rvsc.2025.105668\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Hip dysplasia (HD) is one of the most prevalent orthopedic issues in dogs. Generic shelf implants are 3D-printed devices designed to address HD in dogs of varying sizes and hip laxity scores. This pilot study evaluated the feasibility and effectiveness of generic shelf implants in six dogs diagnosed with bilateral HD. Each dog underwent bilateral hip surgery in a single session followed by a 12-month monitoring period.</div><div>Post-operative CT scans revealed increased femoral head coverage in all 12 hips, resulting in reversed hip laxity. However, implants exhibited positional deviations from optimal congruency for 5.1 ± 1.7 mm. Mild to moderate osteoarthritis (OA) progression was observed during the lead times and post-operatively. Although force plate analysis showed no significant changes, functional outcomes improved, as demonstrated by reduced owner questionnaire scores at 12 months post-surgery. Post-operative internal rotation and abduction angles were reduced compared to pre-operative values, suggesting potential impingement due to implant positioning. Complications were observed in one dog (two hips). Another dog died nine months post-surgery due to unrelated causes. Post-mortem histology and micro-CT analysis of these hip joints revealed localized cartilage depletion around the implant's rim extension area. However, no lameness or hip discomfort was reported by the owner before the dog's death.</div><div>The generic shelf implant effectively enhances hip stability and alleviates pain-related behaviors by improving femoral head coverage. Suboptimal placement was associated with reduced range of motion and OA progression in this study. Refinements to the implant design and adjusting sizing protocols to better match acetabular morphology are necessary.</div></div>\",\"PeriodicalId\":21083,\"journal\":{\"name\":\"Research in veterinary science\",\"volume\":\"191 \",\"pages\":\"Article 105668\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-04-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research in veterinary science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0034528825001420\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research in veterinary science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0034528825001420","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Pilot study on the use of an off-the-shelf 3D-printed titanium acetabular rim extension implant for treating canine hip dysplasia
Hip dysplasia (HD) is one of the most prevalent orthopedic issues in dogs. Generic shelf implants are 3D-printed devices designed to address HD in dogs of varying sizes and hip laxity scores. This pilot study evaluated the feasibility and effectiveness of generic shelf implants in six dogs diagnosed with bilateral HD. Each dog underwent bilateral hip surgery in a single session followed by a 12-month monitoring period.
Post-operative CT scans revealed increased femoral head coverage in all 12 hips, resulting in reversed hip laxity. However, implants exhibited positional deviations from optimal congruency for 5.1 ± 1.7 mm. Mild to moderate osteoarthritis (OA) progression was observed during the lead times and post-operatively. Although force plate analysis showed no significant changes, functional outcomes improved, as demonstrated by reduced owner questionnaire scores at 12 months post-surgery. Post-operative internal rotation and abduction angles were reduced compared to pre-operative values, suggesting potential impingement due to implant positioning. Complications were observed in one dog (two hips). Another dog died nine months post-surgery due to unrelated causes. Post-mortem histology and micro-CT analysis of these hip joints revealed localized cartilage depletion around the implant's rim extension area. However, no lameness or hip discomfort was reported by the owner before the dog's death.
The generic shelf implant effectively enhances hip stability and alleviates pain-related behaviors by improving femoral head coverage. Suboptimal placement was associated with reduced range of motion and OA progression in this study. Refinements to the implant design and adjusting sizing protocols to better match acetabular morphology are necessary.
期刊介绍:
Research in Veterinary Science is an International multi-disciplinary journal publishing original articles, reviews and short communications of a high scientific and ethical standard in all aspects of veterinary and biomedical research.
The primary aim of the journal is to inform veterinary and biomedical scientists of significant advances in veterinary and related research through prompt publication and dissemination. Secondly, the journal aims to provide a general multi-disciplinary forum for discussion and debate of news and issues concerning veterinary science. Thirdly, to promote the dissemination of knowledge to a broader range of professions, globally.
High quality papers on all species of animals are considered, particularly those considered to be of high scientific importance and originality, and with interdisciplinary interest. The journal encourages papers providing results that have clear implications for understanding disease pathogenesis and for the development of control measures or treatments, as well as those dealing with a comparative biomedical approach, which represents a substantial improvement to animal and human health.
Studies without a robust scientific hypothesis or that are preliminary, or of weak originality, as well as negative results, are not appropriate for the journal. Furthermore, observational approaches, case studies or field reports lacking an advancement in general knowledge do not fall within the scope of the journal.