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系统性红斑狼疮患者停用免疫抑制剂的风险和益处

IF 29.4 1区 医学 Q1 RHEUMATOLOGY
Nature Reviews Rheumatology Pub Date : 2025-05-02 DOI:10.1038/s41584-025-01262-5
Catriona A. Wagner, Judith A. James
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引用次数: 0

摘要

在系统性红斑狼疮中撤销免疫抑制治疗可降低毒性并改善缓解期患者的生活质量，但存在疾病再激活的风险。新出现的研究强调了使用临床标准和分子谱来指导个性化策略确定可以安全停止治疗的患者的重要性。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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Risks and benefits of immunosuppressant withdrawal in systemic lupus erythematosus
Withdrawing immunosuppressive treatment in systemic lupus erythematosus offers reduced toxicity and improved quality of life for patients in remission but carries a risk of disease reactivation. Emerging studies emphasize the importance of identifying patients who can safely discontinue therapy using clinical criteria and molecular profiling to guide personalized strategies.
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来源期刊
Nature Reviews Rheumatology
Nature Reviews Rheumatology 医学-风湿病学
CiteScore
29.90
自引率
0.90%
发文量
137
审稿时长
6-12 weeks
期刊介绍： Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.
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