Desiree R. Azizoddin, Jian Zhao, Sara M. DeForge, Meng Chen, Ryan Nipp, Jennifer Hardcopf Stagg, Kerry Bond, Raina Leckie, Blake T. Hilton, Jordan M. Neil, James A. Tulsky, William Pirl, Robert R. Edwards, Beth D. Darnall
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We evaluated the intervention's preliminary feasibility and acceptability for patients with cancer-related pain.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Adults with cancer-related pain (≥ 4/10, average pain) who are receiving cancer treatment (<span><</span> 3 months) self-enrolled or were recruited from the Stephenson Cancer Center (SCC) in Oklahoma. Patients completed a baseline survey and attended the 90-min group-based, Zoom-delivered telehealth intervention. They completed post-intervention, 2-week, and 4-week follow-up assessments and an optional debriefing interview. The feasibility benchmark was ≥ 70% attendance and 80% of acceptability items rated ≥ 4/5.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Seventy participants (67.5% female; mean age = 52.5 years; 25% rural-dwelling) enrolled. Forty of 70 (57%) attended the intervention. Of those, 95% completed the post-intervention survey, and 90% and 95% completed the 2-week and 4-week follow-ups, respectively. Participants reported high acceptability, understandability (97%), and relevance (90%). Most (80%) would recommend the class to others. Qualitative feedback highlighted reduced helplessness and fear regarding opioid use, adoption of behavioral pain management strategies, and appreciation for the convenience of telehealth. Exploratory analyses showed significant reductions in pain intensity (mean difference [MD] = 1.27, <i>p</i> = 0.001), pain interference (MD = 5.48, <i>p</i> = 0.017), pain catastrophizing (MD = 6.0, <i>p</i> = 0.003), sleep disturbance (MD = 3.64, <i>p</i> = 0.004), and depression (MD = 3.97, <i>p</i> = 0.018) at 4 weeks.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>While attendance was below feasibility benchmarks, this interdisciplinary, telehealth intervention was acceptable and improved self-reported cancer pain management. Further research will identify barriers to improve attendance, and determine the optimal timing within the cancer trajectory to deliver pain self-management content. 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The feasibility benchmark was ≥ 70% attendance and 80% of acceptability items rated ≥ 4/5.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Seventy participants (67.5% female; mean age = 52.5 years; 25% rural-dwelling) enrolled. Forty of 70 (57%) attended the intervention. Of those, 95% completed the post-intervention survey, and 90% and 95% completed the 2-week and 4-week follow-ups, respectively. Participants reported high acceptability, understandability (97%), and relevance (90%). Most (80%) would recommend the class to others. Qualitative feedback highlighted reduced helplessness and fear regarding opioid use, adoption of behavioral pain management strategies, and appreciation for the convenience of telehealth. 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引用次数: 0
摘要
癌症患者获得综合疼痛治疗的机会有限。我们开发了一个90分钟，单次，远程医疗，跨学科的干预，结合了癌症特定的医学教育和行为疼痛治疗。我们评估了癌症相关疼痛患者干预的初步可行性和可接受性。方法正在接受癌症治疗（3个月）的患有癌症相关疼痛（≥4/10，平均疼痛）的成人自行注册或从俄克拉何马州斯蒂芬森癌症中心（SCC）招募。患者完成了一项基线调查，并参加了90分钟的以小组为基础的zoom提供的远程医疗干预。他们完成了干预后、2周和4周的随访评估和可选的述职面谈。可行性基准为出勤率≥70%，80%可接受项目评分≥4/5。结果70例，女性占67.5%；平均年龄52.5岁；25%农村居民)入学。70人中有40人（57%）参加了干预。其中95%完成干预后调查，90%和95%分别完成2周和4周随访。参与者报告了较高的可接受性、可理解性（97%）和相关性（90%）。大多数（80%）会向他人推荐该课程。定性反馈强调减少了对阿片类药物使用的无助感和恐惧，采用了行为疼痛管理策略，并对远程保健的便利性表示赞赏。探索性分析显示，在4周时，疼痛强度（平均差值[MD] = 1.27, p = 0.001）、疼痛干扰（MD = 5.48, p = 0.017）、疼痛灾难化（MD = 6.0, p = 0.003）、睡眠障碍（MD = 3.64, p = 0.004）和抑郁（MD = 3.97, p = 0.018）显著降低。结论虽然出勤率低于可行性基准，但这种跨学科的远程医疗干预是可接受的，并改善了自我报告的癌症疼痛管理。进一步的研究将确定提高出勤率的障碍，并确定在癌症轨迹内提供疼痛自我管理内容的最佳时机。需要随机对照试验来评估干预对患者预后的效果。
Initial Feasibility and Acceptability of Cancer Pain 101: An Interdisciplinary, Single-Session, Telehealth Intervention for Patients With Cancer-Related Pain
Introduction
Patients with cancer have limited access to comprehensive pain treatment. We developed a 90-min, single-session, telehealth, interdisciplinary intervention that combines cancer-specific medical education and behavioral pain treatment. We evaluated the intervention's preliminary feasibility and acceptability for patients with cancer-related pain.
Methods
Adults with cancer-related pain (≥ 4/10, average pain) who are receiving cancer treatment (< 3 months) self-enrolled or were recruited from the Stephenson Cancer Center (SCC) in Oklahoma. Patients completed a baseline survey and attended the 90-min group-based, Zoom-delivered telehealth intervention. They completed post-intervention, 2-week, and 4-week follow-up assessments and an optional debriefing interview. The feasibility benchmark was ≥ 70% attendance and 80% of acceptability items rated ≥ 4/5.
Results
Seventy participants (67.5% female; mean age = 52.5 years; 25% rural-dwelling) enrolled. Forty of 70 (57%) attended the intervention. Of those, 95% completed the post-intervention survey, and 90% and 95% completed the 2-week and 4-week follow-ups, respectively. Participants reported high acceptability, understandability (97%), and relevance (90%). Most (80%) would recommend the class to others. Qualitative feedback highlighted reduced helplessness and fear regarding opioid use, adoption of behavioral pain management strategies, and appreciation for the convenience of telehealth. Exploratory analyses showed significant reductions in pain intensity (mean difference [MD] = 1.27, p = 0.001), pain interference (MD = 5.48, p = 0.017), pain catastrophizing (MD = 6.0, p = 0.003), sleep disturbance (MD = 3.64, p = 0.004), and depression (MD = 3.97, p = 0.018) at 4 weeks.
Conclusion
While attendance was below feasibility benchmarks, this interdisciplinary, telehealth intervention was acceptable and improved self-reported cancer pain management. Further research will identify barriers to improve attendance, and determine the optimal timing within the cancer trajectory to deliver pain self-management content. Randomized controlled trials are needed to assess intervention efficacy on patient outcomes.
期刊介绍：
Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas:
Clinical Cancer Research
Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations
Cancer Biology:
Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery.
Cancer Prevention:
Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach.
Bioinformatics:
Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers.
Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.
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