成功管理的增殖性门孢子虫感染性关节炎和骨髓炎在免疫能力的儿童：一个案例报告

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Medical Mycology Case Reports Pub Date : 2025-04-25 DOI:10.1016/j.mmcr.2025.100704

Niall Johnston , Bradley Rockliff , Robert Duguid , Pamela Palasanthiran , Adam W. Bartlett , Phoebe CM. Willams , Brendan J. McMullan

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引用次数: 0

摘要

我们报告一例危及肢体的增殖性Lomentospora肘感染在一个3岁的免疫功能正常的男孩后闭合性骨折。通过联合积极清创、联合抗真菌治疗、伏立康唑骨水泥和消毒关节冲洗，感染得以解决。这突出了早期诊断和多模式手术、医疗和其他新型辅助治疗来管理这些难以治疗的感染的必要性。加强研究和改善新型抗真菌药物的可及性对于加强对多重耐药真菌感染的治疗选择至关重要。

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Successful management of Lomentospora prolificans septic arthritis and osteomyelitis in an immunocompetent child: A case report

Available online We report a case of limb-threatening Lomentospora prolificans elbow infection in a 3-year-old immunocompetent boy following a closed fracture. Resolution of infection was achieved following combined aggressive debridement, combined antifungal therapy, voriconazole-loaded bone cement, and antiseptic joint irrigation. This highlights the need for early diagnosis and multi-modal surgical, medical and other novel adjunctive therapies in managing these difficult-to-treat infections. Increased research and improved access to novel antifungal drugs are essential to enhance treatment options for intrinsically multidrug-resistant fungal infections.

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来源期刊

Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

47 days