抗生素降低婴儿的疫苗反应

IF 58.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2025-04-30 DOI:10.1038/d41591-025-00028-6

引用次数: 0

摘要

新生儿抗生素暴露被发现对疫苗反应产生负面影响，可能是由双歧杆菌水平降低介导的——这突出了提高婴儿疫苗效力的潜在策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Antibiotics reduce vaccine responses in infants

Neonatal antibiotic exposure was found to negatively impact vaccine responses, probably mediated by decreased Bifidobacterium levels — which highlights potential strategies for enhancing vaccine efficacy in infants.

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

期刊介绍： Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.